Interdisciplinary Neuroscience: Seminars/Events

Multimodal Preclinical Imaging of Neurophysiological Signatures in the BOLD MRI Signal

Presented by Shella Keilholz 

Thursday, Dec. 9, 4 p.m.


STAR Tower Audion

Newark, DE

The brain has all the hallmarks of a complex system, with meaningful activity occurring at a wide range of spatial and temporal scales. When measured with resting state fMRI, all of this activity is compressed into a single measurement of the resulting hemodynamic response for each voxel at each time point. However, using multimodal preclinical neuroimaging techniques and leveraging the spatial, temporal and spectral properties of different types of activity, we may be able to identify signatures in the rs-fMRI signal. In this talk, Shella Keilholz will describe types of activity that we expect to contribute to the rs-fMRI signal and features that might allow us to selectively extract them for use in research or the clinic.


Keilholz obtained her B.S. in Physics from the University of Missouri—Rolla (now Missouri University of Science and Technology). Her doctorate in Engineering Physics at the University of Virginia focused on quantitative measurements of perfusion with arterial spin labeling MRI. After graduation, she went to the NIH as a postdoctoral researcher in Alan Koretsky’s lab to learn functional neuroimaging. She is currently a professor in the joint Emory University/Georgia Tech Biomedical Engineering department. Her research seeks to elucidate the neuropsychological processes that underlie the BOLD signal and develop analytical techniques that leverage spatial and temporal information to separate contributions from different sources.



Upcoming Seminars


New Date: TBA:

Ho Ming Chow - Communication and Science Disorders: "The Neurobiology of Developmental Stuttering"

Jen Semrau - Kinesiology and Applied Physiology: “The utility of robotics for upper limb assessment and treatment after stroke”

Jackie Schwarz - Psychological and Brain Sciences: "Developmental Neuroimmunology and Behavior"


New Date: TBA:

Curtis Johnson - Biomedical Engineering: “Mechanical Brain Mapping in Aging and Development with MR Elastography"

Lisha Shao - Biological Sciences: “A neural circuit encoding the sensory experience of copulation in female Drosophila”

Amy Griffin -  Psychological and Brain Sciences: "Examining the role of the thalamus in higher-order cognition"

If you have any questions about these seminars, please contact Cindy King.