CHEM-527   FALL 1999

INTRODUCTORY BIOCHEMISTRY

TENTATIVE SCHEDULE

The following schedule is subject to minor changes and will be up dated regularly. The order of topics follows the sequence of chapters in the textbook, Principles of Biochemistry, by Horton et al. A supplemental textbook, Molecular Aspects of Cell Biology by Garrett and Grisham, will be used during the last third of the course. An optional problem session will be held each Thursday evening from 7 to 10 in 102 Gore Hall except on weeks when there are Thursday Hourly Exams.
 
Tuesdays Thursdays Problem Session Problems
Aug. 31 Introduction to the Course.
(Chapter 1)
Sept. 2 Water 
(Chapter 2)
Interdisciplinary water problem Hot-Headed Moles in Antarctica.
Sept. 7 Amino Acids and Protein Primary Structure.  (Chapter 3) Sept. 9 Protein Structure and Function. 
(Chapter 4)
Analysis of Hemoglobin Variants. (Problem 1a)
ATCase Electrophoresis (Problem 1b)
Sept. 14 Properties of Enzymes. 
(Chapter 5)
Sept. 16   Hurricane Floyd - Class and Problem session canceled Inhibition of Proline Racemase (Problem 2)
Sept. 21 Mechanism of Enzymes. 
(Chapter 6)
Sept. 23 Coenzymes  (Chapter 7) NAD & NADP (Problem 3a)
Sept. 28 Carbohydrates  (Chapter 8) and Nucleotides (Chapter 9) Sept. 30 Lipids and Membranes. 
(Chapter 10)
Review Session 
TPP and Carbohydrates (Problem 3b)
Oct. 5 Introduction to Metabolism. (Chapter 11) Oct. 7 First Hourly Exam
(Chapters 1 - 10)
Special Review Session Tuesday, Oct.5, 7 - 9 PM 115 Gore Hall
Oct. 12 Glycolysis (Chapter 12)
Ms. Irene Rudik, Lecturer 
Oct. 14 Citric Acid Cycle (Chapter 13)
Ms. Irene Rudik, Lecturer 
Glucose Metabolism (Problem 4)
Oct. 19 Other Carbohydrate Metabolism. (Chapter 14) Oct. 21 Electron Transport & Oxidative Phosphorylation    (Chapter 15) Photosynthesis Case Page 1,2,3,4,5. Riboflavin Biosynthesis (Problem 5)
Oct. 26 Photosynthesis
(Chapter 16)
Oct. 28 Lipid Metabolism
(Chapter 17)
Fatty Acid Metabolism  (Problem 6a)
HMG-CoA Reactions (Problem 6b)
Nov. 2 Amino Acid Metabolism.
(Chapter 18)
Nov. 4 Second Hourly Exam
(Chapters 11 - 17)
Special Review Session Tuesday
Nov. 2, 7 - 9 PM 115 Gore Hall
Nov. 9 Nucleotide Metabolism. 
(Chapter 19)
Nov. 11 Nucleic Acids
(Chapter 20)
Lys Biosynthesis in Fungi (Problem 7a)
Amino Acid Case Study Page 1,2,3,4
Nov. 16 DNA Replication, Repair, & Recombination. (Chapter 21) Nov. 18 Transcription and RNA Processing.
(Chapter 22)
Mutational Analysis (Problem 8a)
Codon Utilization (Problem 8b)
Nov. 23 Protein Synthesis.
(Chapter 23)
Nov. 25 THANKSGIVING BREAK No Problem Session
Attenuation Problem
Nov. 30 Recombinant DNA Technology. (Chapter 24) Dec. 2 Third Hourly Exam
(Chapters 18 - 23)
Special Review Session Tuesday November 30, 7 - 9 PM 115 Gore Hall
Dec. 7 Signal Transduction Dec. 9 Biochemical Evolution Final Exam 3:30 - 6:30 
Thursday, December 16



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Last updated: 27 February 2000 by Hal White
Copyright 1999, Department of Chemistry and Biochemistry, University of Delaware, Newark, DE  19716