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INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2012 |
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INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2012 |
The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.
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| August 29 Intro. and Review of Metabolic Principles |
August 31 ATP and Bioenergetics Energy Charge, and Adenylate Metabolism. |
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| September 3 Labor Day - Holiday |
September 5 Form Groups, Group work on metabolic reactions involving pyruvate. |
September 7 Inborn Errors of Metabolism - Assignment due Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes |
| September 10 Lactose structure and metabolism Pentose Phosphate Pathway (oxidative branch) |
September 12 Pentose Phosphate Pathway (non-oxidative branch) NAD vs NADP in Redox Reactions |
September 14
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| September 17 Go over Homework Problem set 2 Wrap up Life Without Oxygen problem, 3, Summary |
September 19 Are you what you eat? Page 1 Read text chapter on Photosynthesis for Friday Calvin Cycle |
September 21 Are you what you eat? Page 2 Visit from Dr. Steve Brohawn (UD Biochem '06, PhD MIT) K+ Channels |
| September 24 Are you what you eat? Page 3 & 4 |
September 26 Are you what you eat? Page 5 |
September 28 Concluding Discussions, Summary |
| October 1 Group quiz on Glycolysis and Photosynthesis |
October 3 Intro to Fatty Acid Structure and Nomenclature Fatty acid oxidation Fatty Acid Synthesis vs Degradation Coenzyme A structure and function |
October 5 Ketone Body Metabolism Propionyl CoA Metabolism Coenzyme B12 Lipid Metabolism - Problems due |
| October 8 Citrate-pyruvate Cycle Glyceride Metabolism |
October 10 Steroid and Isoprenoid Biosynthesis Overview of Isoprenoid metabolism HMG-CoA and IPP synthesis |
October 12 Rxns of HMGCoA - Problem due Wrap up lipid metabolism The Nitrogen Cycle Intorduction to nitrogen fixation |
| October 15 Conceptual Class Activity on Modular assembly and self assembly in biosynthesis |
October 17 Nitrogenase Nitrate and Nitrite Reduction Molybdopterin Intro. Amino Acid Metabolism Nitrogen Acquisition and Excretion |
October
19 Lysine Biosynthesis - Problem due Ammonium entry into metabolism Glutamine Synthetase and its Regulation Pyridoxal Phosphate (PLP) |
| October 22 Glutamate Family of Amino Acids Synthesis of Proline from Glutamate Synthesis of Arginine from Glutamate via Ornithine |
October 24 Flux in Metabolism Oxaloacetate Family of Amino Acids Regulation of Branched Biosynthetic Pathways |
October 26 Biosynthesis of Essential Amino Acids - due Generation of Formyl and Methyl Groups- Folate Metabolism Urea Cycle Amino Acid Catabolism |
| October 29 University Classes Cancelled due to Hurricane Sandy |
October 31 University Classes Cancelled due to Hurricane Sandy |
November 2 No class, Midterm Exam Review session. Sunday, November 4, 7:30-9:30PM in 205 Brown Laboratory. |
| November
5 Human Starvation Metabolic Limits of Human Performance |
November 7 Midterm Exam 8:00 am - 10 am |
November 9 Plant vs Animals in the Dining Hall. Page 1 |
| November 12 Plant vs Animals in the Dining Hall. Page 2 |
November 14 Plant vs Animals in the Dining Hall Page 3 |
November 16 Plant vs Animals in the Dining Hall. Page 4, Page 5, and Summary |
| November 19 Begin Final Group Project |
November 21 Thanksgiving Break |
November 23 Thanksgiving Break |
| November 26 Group Project |
November 28 Group Project |
November 30 Group Project |
| December 3 Group Project due Group Project Presentations |
December 5 & 6 (hurricane
makeup day) Group Project Presentations On-line course evaluations due |
Final
Exam 3:30-6:30 PM Wednesday, December 12 in 207 Brown Laboratory |
