Diagnosis: acute interstitial nephritis
Here is why...
Acute interstitial nephritis (AIN) can result from an allergic reaction to a drug. Our patient was taking phenoxymethylpenicillin, a type of penicillin, for his mouth abscess. Penicillin is associated with AIN because it commonly causes an immune response in patients. Penicillin is removed from the body when it is filtered through the tubules of the nephron. The immune response of the renal tubular epithelium inadvertently injures the nephron.
Symptoms of AIN due to an allergic reaction
On the body:
fever
skin rash
In the urinalysis:
mild proteinuria
variable degrees of
hematuria
variable degrees of
leukocyturia
presence of casts (leukocyte,
granular, hyaline, and renal cell)
renal epithelial cells
drug crystals