2. If the young patient has hypertension, what affects would this have on cast formation in correlation with the evidence provided?

Answer:
Hypertension affects the ability of the kidneys to remove the body's wastes from the blood, resulting in less waste being filtered.  The addition of decreased urine flow or output, due to the patient's pyelonephritis, allows for the proper conditions for cast formation.  Therefore, the presence of white blood cell casts is caused by the patient's acute pyelonephritis.


Hypertension also causes a risk of proteinuria.  In this case, the stix result for protein provides further evidence that the young patient definitely has proteinuria.  Proteinuria can in effect cause granular cast formation, hence the presence of granular casts in the patient's urine.

formed element      formed element
                White Blood Cell Cast                     Granular Cast
                     Copyright© Mary Ann McLane

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