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Middle-Aged Woman with Dark Urine


4. Is it possible to have amorphous from the two major crystal types below? Why or why not? What is in this photomicrograph which indicates it definitely could not be from this patient?

ammonium biurate, triple phosphate, and bacteria

The two classical crystals represented here are ammonium biurate (dark, thorny-apple type crystal), and triple phosphate (clear, coffin-like crystal). They are two crystals which can exist in alkaline urine; therefore, it is possible that they could be the cause for the amorphous in the sample. The presence of bacteria indicates this is definitely not the patient's urine.

Back to the questions






A 35 year old woman went to the doctor complaining of fatigue, shortness of breath, and dark urine. Her skin was very pale, and the whites of her eyes were slightly yellow. She reported recently having a sinus infection which was treated with penicillin. Urinalysis results are:

Color
dark red/brown
Protein
100mg/dL (2+)
Blood
large
Appearance
clear
Glucose
negative
Urobilinogen
12.0 EU
Sp. Gravity
1.020
Ketones
negative
Nitrite
negative
pH
8.0
Bilirubin
negative
Leukocyte
negative

Microscopic
amorphous 2+
hemosiderin granules present

Upon receiving the urinalysis results, the physician orders a blood test for haptoglobin which comes back less than 5 mg/dL (reference range = 26-185 mg/dL).



   


 



Colleen Carey | Honors Urinalysis | Fall 2005