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Middle-Aged Woman with Dark Urine


3. Would you expect to see the following formed element? Why or why not?

granular cast

The formed element pictured is a granular cast. In order to have a cast form, the patient must have elevated dissolved solute, slowed urine flow, and acidic urine. While there was elevated protein in the patient, the urine pH was 8.0, which means the urine was alkaline. For this reason, the granular cast above would probably not be found in this patient's urine.




A 35 year old woman went to the doctor complaining of fatigue, shortness of breath, and dark urine. Her skin was very pale, and the whites of her eyes were slightly yellow. She reported recently having a sinus infection which was treated with penicillin. Urinalysis results are:

Color
dark red/brown
Protein
100mg/dL (2+)
Blood
large
Appearance
clear
Glucose
negative
Urobilinogen
12.0 EU
Sp. Gravity
1.020
Ketones
negative
Nitrite
negative
pH
8.0
Bilirubin
negative
Leukocyte
negative

Microscopic
amorphous 2+
hemosiderin granules present

Upon receiving the urinalysis results, the physician orders a blood test for haptoglobin which comes back less than 5 mg/dL (reference range = 26-185 mg/dL).




   




Colleen Carey | Honors Urinalysis | Fall 2005