CHECKLIST
This
form is a routing document for the approval of new and revised academic
programs.Page 2 will serve as an
attachment to the Faculty Senate agenda.Proposing
department should complete form, attach as a cover page and forward to
the college dean. Documentation should include copy of curriculum as it
is to appear in the Undergraduate and Graduate Catalog.Proposals
must arrive to the Undergraduate/Graduate Committee by November in order
to reach the Faculty Senate by March 1.Proposals
received after this date cannot be implemented the following year nor included
in the catalog for that year.
1.Proposed
change leads to the degree of
()
Bachelor of Arts()
Master of Arts()
Doctor of Philosophy
(X)
Bachelor of Science()
Master of Science()
Other ______________________________________
2.()
New major/curriculum Title
to be entered in record of students who select this program
()
New minor Title
to be entered in record of students who select this program
()
Change from provisional to permanent status.
3.(X)
Revision of existing:(X) major()
minor()
concentration
Present
title Biochemistry
Records
System Program Code
(X)
Add/delete required courses/credit hours
()
Add concentration Title
()
Delete concentration Title
4.()
Deletion of existing/disestablish:()
major()
minor(
) Other _______________________________
Title Code______________________
5.()Policy
Change____________________________________________________________________________________
Title/Department
ROUTING
AND APPROVALS: (Please do not remove supporting documentation.)
Department
Chairperson Date
Dean
of CollegeDate
Chairperson,
Senate Com. On UG or GR StudiesDate
Chairperson,
Senate Coordinating Com.Date
Secretary,
Faculty SenateDate
Date
of Senate ResolutionDate
to be Effective
RegistrarProgram
CodeDate
Vice
Provost for Academic Programs & PlanningDate
ProvostDate
Board
of Trustee NotificationDate
a.Rationale
for creation, revision, ordeletion:
Since
its inception in 1989 and its approval for permanent status in 1994, the
Biochemistry BS major has grown to produce 20 to 35 graduates per year
of which about 40% entered the University of Delaware as honors students.
The Biochemistry curriculum has not been reviewed since 1994. Changes in
the course offerings and curricula in the Department of Biological Sciences
have affected the elective options for Biochemistry majors and have necessitated,
in part, the curriculum revisions proposed here. As detailed below, these
include a decrease in the elective course options in Biology, addition
of a required course in chemistry, and the initiation of a research requirement
that can be satisfied in several ways.In
conjunction with these revisions, are revised descriptions of several courses
and requests for permanent status for several courses offered for several
years.
Revision
of acceptable Laboratory Experience Options: Recently,
the Biology Department created a BS major in Cell , Molecular Biology,
& Genetics. In doing so, several four-credit courses (BISC-301, 303,
& 306), which previously had laboratory components, were restructured
into three-credit lecture-only courses (BISC-401, 403, 306). Concomitantly,
Biology created several two-credit investigative laboratory courses (including
BISC-315, 411, 413). While Biochemistry majors may still take the new lecture
courses, Biological Science majors have priority for the limited enrollment
laboratory courses. Furthermore, the greater number of credits for the
new laboratory courses reduces their accessibility to Biochemistry majors
who have relatively few elective credits. As originally conceived, the
previous offerings of Biology courses with laboratory components had provided
an alternative for students who did not chose to do undergraduate research
(CHEM-468). From the previous
list of courses, the following courses should be retained: BISC-300, Microbiology
and BISC-601, Immunochemistry. In
addition, the following courses are also acceptable, but space is limited:
BISC-315, Experimental Cell Biology, BISC-411, Molecular Biology of the
Cell Laboratory; BISC-413, Advanced Genetics Laboratory.
Requirement
for CHEM-643, Intermediary Metabolism: Heretofore,
Biochemistry majors were required to take CHEM-641 and CHEM-642, a two-semester
biochemistry sequence. The second semester of this sequence included metabolism
for the first half and molecular biology topics in the second half. The
enormous increase in information in the molecular biosciences necessitates
splitting out the metabolism component and limiting the content in CHEM-642
to topics related to DNA, RNA, and protein synthesis.To
accommodate the loss of metabolic topics from CHEM-642, Intermediary Metabolism
(CHEM-643), an existing course, will become a required course for Biochemistry
majors and will be taught every fall rather than its previous offering
in alternate years. Offering a three-semester biochemistry sequence is
now standard at several schools including the University of Maryland.
Advanced
Course Options: The
introduction of a research requirement and CHEM-643 necessitates a change
in the advanced course options for Biochemistry majors to the following:
Two CHEM-6XX courses or Biology courses selected from among the following:
BISC-300, Introduction to Microbiology; BISC-306, General Physiology; BISC-401,
Molecular Biology of the Cell; BISC-403, Genetics and Evolutionary Biology;
BISC-601, Immunochemistry; BISC-654, Biochemical Genetics; BISC-679, Virology.
Renumbering
of provisional Biochemistry Courses:The
following courses have been offered for several years under the experimental
course numbers CHEM-467 or CHEM-667. We wish to give these courses permanent
status and include them as elective options in Biochemistry curriculum.
CHEM-401Tutorial
Methods of Instruction (1-2 credits)
Co-requisite:Being
a Tutor-Facilitator in a PBL course.
Description:
For juniors and seniors who are group tutor-facilitators in courses where
problem-based learning (PBL) is used as a mode of instruction.
CHEM-645
Protein Structure and Function (3 credits)
Prerequisites:
CHEM-641
Description:
Overview of structural biology, including how x-ray crystallography, NMR
spectroscopy, homology modeling and other techniques are used to solve
or model structures of macromolecules. Representative proteins will be
discussed in terms of how a protein’s structure relates to its function.
CHEM-646
DNA-Protein Interactions (3 credits)
Prerequisites:
CHEM-642
Description:
Current Topics of DNA-protein interactions which focus on DNA replication,
DNA recombination, DNA damage repair, transcription and translation processes.
CHEM-649
Molecular Biophysics (3 credits)
Prerequisites:
CHEM-641
Description:
Biophysical principles and methods: thermodynamic and kinetic analysis
of folding; protein-nucleic acid interactions; ligand binding; spectroscopy;
structural methods; modeling; calorimetry; ultracentrifugation; SPR. Problem
solving in macromolecular interactions: protein refolding; altering ligand
affinity; increasing protein stability; drug design and HTS; protein expression
and solubility; protein engineering.
b.Summary
of program: The
undergraduate biochemistry curriculum prepares majors for employment and
post-graduate studies in the molecular biosciences or medicine.
MAJOR:
BIOCHEMISTRY
CURRICULUMCREDITS
UNIVERSITY
REQUIREMENTS
ENGL
110Critical Reading and Writing
(minimum gradeC-). 3
Three
credits in an approved course or courses stressing... 3
multicultural,
ethnic, and/or gender-related content (see p. 57).
COLLEGE
REQUIREMENTS
WRITING: (minimum
grade C-)............... 3
A
second writing course involving significant writing experience
including
two papers with a combined minimum of 3,000 words to be submitted for extended
faculty critique of both composition and content.This
course must be taken after completion of 60 credit hours.Appropriate
writing courses are normally designated in the semester=s
Registration Booklet.(See list of
courses approved for second writingrequirement,
page 83.)
Foreign
Language:0-12
Completion
of the intermediate-level course (107 or 112) in a modern foreign language.Number
of credits needed and initial placement depends on number of years of high
school study of foreign language.Students
with four or more years of high school work in a single modern foreign
language may attempt to fulfill the requirement in that language by taking
an exemption examination.(German
recommended)
Breadth
Requirement
(See p. 85)
A
total of twenty-one credits from Groups A, B and C is .......... 21
required
with a minimum of six credits in each group.The
six credits from each group could be from the same area.
Group
A: Understanding
and appreciation of the creative arts and humanities.
Grpup
B: The study
of culture and institutions over time.
Group
C: Empirically
based study of human beings and their environment.
MAJOR
REQUIREMENTS
Minimum
46 credits total in CHEM
CHEM
111/112 General Chemistry 6
CHEM
119/120 Quantitative Chemistry I and II . 5
CHEM
331/332 Organic Chemistry 6
CHEM
333/334 Organic Chemistry Majors Laboratory I and II ................... 4
CHEM
342 Introduction to Biochemistry........ 3
CHEM
418 Introductory Physical Chemistry I .......... 3
or
CHEM
443 Physical Chemistry
CHEM
437/438 Instrumental Methods and Laboratory ...... 4
CHEM
641 Biochemistry ........ 3
CHEM
419 Introductory Physical Chemistry II ......... 3
or
CHEM
444 Physical Chemistry
CHEM
445 Physical Chemistry Laboratory ............................ 1
CHEM
642 Biochemistry ........ 3
CHEM
643 Intermediary Metabolism ........... 3
Two
Advanced Chemistry courses at 600-level .............. 6
or
Two
Biology courses selected from the following: ........... 6-8
BISC
300 Introduction to Microbiology......... 4
BISC
306 General Physiology ........... 3
BISC
401 Molecular Biology of the Cell . 3
BISC
403 Genetics and Evolutionary Biology ................ 3
BISC
601 Immunochemistry . 4
BISC
654 Biochemical Genetics ............................ 3
BISC
679 Virology ............................ 3
CHEM
465 Seminar (two semesters) .... 2
CHEM
468 Undergraduate Research ............. 6
or
Two
Biology laboratory courses selected from the following: ...... 4-8
BISC
300 Introduction to Microbiology......... 4
BISC
315 Experimental Cell Biology ................ 2
BISC
411 Molecular Biology of the Cell Laboratory ............ 2
BISC
413 Advanced Genetics Laboratory............ 2
BISC
601 Immunochemistry . 4
Related
Work
MATH-241
Analytic Geometry and Calculus A ............ 4
MATH-242
Analytic Geometry and Calculus B (strongly recommended ....... 4
BISC
207/208 Introductory Biology I and II ................... 8
PHYS
201/202 Introductory Physics I and II ................... 8
ELECTIVES
After
required courses are completed, sufficient elective credits must be taken
to meet the minimum credit requirement for the degree.
CREDITS
TO TOTAL A MINIMUM OF .... 127
Candidates
for a B.S. in biochemistry must achieve a cumulative GPA of at least 2.00
for all chemistry courses taken.Repeated
chemistry courses are counted only once in the calculation of the Chemistry
GPA.The calculation of the chemistry
course GPA (2.00 minimum required for graduation) for candidates for the
B.S. degree in Chemistry or Biochemistry will not include grades earned
for lower level subdisciplinary courses taken after a higher level
course in the same subdiscipline has been taken and passed with a grade
of C or higher.Likewise, freshman-level
courses may not be used by upperclassmen as GPA enhancers after
those required for graduation has been taken.CHEM
342 and CHEM 100 will be regarded as exceptions to the foregoing prohibitions,
since their subject matter coverage is considerably different than that
found in higher level courses.
Example:
A grade earned in CHEM 214 subsequent to a C or better grade earned in
CHEM 527 (or CHEM 641/642) would not be counted in the chemistry GPA calculation
for B.S. chemistry or biochemistry majors.
Course Requirements for Existing and Revised BS Biochemistry Degree
(Parentheses) represent elective options
|
Major
?
Course? |
Biochem
Current |
Biochem
Proposed |
Notes |
|
ENGL
110
|
3
|
3
|
|
|
Second
Writing
|
3
|
3
|
|
|
Foreign
Language
|
0-12
|
0-12
|
|
|
Breadth
A, B, & C minimum of 6 credits in each
|
21
|
21
|
|
|
CHEM-111/112General
Chemistry I & II
|
6
|
6
|
|
|
CHEM-119/120Quantitative
ChemI & II
|
5
|
5
|
|
|
CHEM-331/332Organic
Chemistry
|
6
|
6
|
|
|
CHEM-333/334Organic
Chem Maj Lab
|
4
|
4
|
|
|
CHEM-342Intro
to Biochemistry
|
3
|
3
|
|
|
CHEM-418Intro
Physical Chemistry I
|
3
or 443
|
3
or 443
|
|
|
CHEM-419Intro
Physical Chemistry II
|
3
or 444
|
3
or 444
|
|
|
CHEM-437/438
Instrumental Analysis & Lab
|
4
|
4
|
|
|
CHEM-443Physical
Chemistry I
|
3
or 418
|
3
or 418
|
|
|
CHEM-444Physical
Chemistry II
|
3
or 419
|
3
or 419
|
|
|
CHEM-445Physical
Chemistry Lab
|
1
|
1
|
|
|
CHEM-465Senior
Seminar
|
2
|
2
|
|
|
CHEM-468Undergraduate
Research
|
(6)
|
(4-8)
|
|
|
CHEM-641Biochemistry
I
|
3
|
3
|
|
|
CHEM-642Biochemistry
II
|
3
|
3
|
|
|
CHEM-643Intermediary
Metabolism
|
(3)
|
3
|
New
requirement
|
|
CHEM-644Mechanisms
of Enzyme Catalysis
|
(3)
|
(3)
|
|
|
CHEM-“645”
Protein Structure and Function
|
(3)
|
(3)
|
667
to regularized course
|
|
CHEM-“646”
DNA-Protein Interactions
|
(3)
|
(3)
|
667
to regularized course
|
|
CHEM-647Biochemical
Evolution
|
(3)
|
(3)
|
|
|
CHEM-648Membrane
Biochemistry
|
(3)
|
(3)
|
|
|
CHEM-“649”Molecular
Biophysics
|
(3)
|
(3)
|
667
to regularized course
|
|
BISC-207/208Introductory
Biology I & II
|
8
|
8
|
|
|
BISC-300Introduction
to Microbiology (has lab)
|
(4)
|
(4)
|
Formerly
BISC-371
|
|
BISC-306General
Physiology
|
(3)
|
(3)
|
Formerly
with lab
|
|
BISC-315
Experimental Cell Biology
|
|
(2)
|
|
|
BISC-401Molecular
Biology of the Cell
|
(3)
|
(3)
|
Formerly
BISC-301 with lab
|
|
BISC-403Genetics
&Evolutionary Biology
|
(3)
|
(3)
|
Formerly
BISC-303 with lab
|
|
BISC-411
Molecular Biology of the Cell laboratory
|
|
(2)
|
|
|
BISC-413
Advanced Genetics Laboratory
|
|
(2)
|
|
|
BISC-601
Immunochemistry
|
(4)
|
(4)
|
|
|
BISC
654Biochemical Genetics
|
(3)
|
(3)
|
|
|
BISC
679Virology
|
(3)
|
(3)
|
|
|
MATH-241
Anal Geometry & Calculus A
|
4
|
4
|
|
|
MATH-242
Anal Geometry & Calculus B
|
(4)
|
(4)
|
Strongly
recommended
|
|
PHYS-201/202
Physics I & II
|
8
|
8
|
|
|
Total
Min Credits with electives
|
127
|
127
|
|
AUTHORIZED
DEGREE TITLES
Please
check the appropriate degree:
()Bachelor
of Applied Science
()Bachelor
of Arts
()Bachelor
of Arts in Educational Studies
()Bachelor
of Arts in Liberal Studies
()Bachelor
of Chemical Engineering
()Bachelor
of Civil Engineering
()Bachelor
of Computer Engineering
()Bachelor
of Electrical Engineering
()Bachelor
of Environmental Engineering
()Bachelor
of Fine Arts
()Bachelor
of Liberal Studies
()Bachelor
of Mechanical Engineering
()Bachelor
of Music
(X)Bachelor
of Science
()Bachelor
of Science in Accounting
()Bachelor
of Science in Agriculture
()Bachelor
of Science in Business Administration
()Bachelor
of Science in Education
() Bachelor
of Science in Nursing
()Masterof
Applied Sciences
()Master
of Arts
()Master
of Arts in Liberal Studies
()Master
of Business Administration
()Master
of Chemical Engineering
()Master
of Civil Engineering
()Master
of Education
()Master
of Electrical Engineering
()Master
of Environmental and Energy Policy
()Master
of Fine Arts
()Master
of Instruction
()Master
of Marine Policy
()Master
of Materials Science and Engineering
()Master
of Mechanical Engineering
()Master
of Music
()Master
of Physical Therapy
()Master
of Public Administration
()Master
of Science
()Master
of Sciencein Nursing
()Doctor
of Education
()Doctor
of Philosophy
This
document will be retained permanently in the Faculty Senate Office.
Revised
04/23/01