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Chemical and Physical Characteristics of Highly Toxic,
Reproductive Toxins and Carcinogenic Materials
The
definitions of these materials are as follows, but consult Chapter 12 of
the Chemical Hygiene Plan (CHP) for further information:
Listed in Appendix E of
the Chemical Hygiene Plan
A chemical
with an:
Oral
LD50 of less than 50 milligrams per kilogram
Absorption
LD50 of less than 200 milligrams per kilograms
Inhalation
LD50 of less than 200 parts per million (PPM)
Regulated
by EHSA or listed by National Toxicology Program (NTP)
and International Agency for Research on Cancer Monographs (IARC) as a
carcinogen:
Overall Evaluations of
Carcinogenicity to Humans
National
Toxicology Program - Report on Carcinogens
Reproductive Toxins
Materials with undesirable reproductive effects can affect both
men and women. As long as there is a potential for conception, the
student or employee must consider the reproductive effects of the
materials they are routinely using.
Mutagens and teratogens are substances that may affect the embryo,
fetus or the exposed person in a manner which produces cancer or disease.
Effects include:
Sterility
Decreased Libido
Impotence
Interrupted Pregnancy (abortion, fetal death, premature delivery)
Birth Defects
Altered Sex Ration
Chromosome Abnormalities
Childhoor Morbidity
Childhood Cancer
Certain chemicals can pass through the breast milk to a nursing child.
Other chemicals can be brought home on clothing and impact the health of
very young children to the unborn child.
Physical hazards can also impact reproductive health.
Researchers
should consult the health hazard and toxicity sections
of the Material Safety Data Sheet for the chemical or substance.
ChemWatch, EHS's
online MSDS Program
Registry of
Toxic Effects of Chemical Substances (RTECS)
State
of California Chemicals Known to the State to Cause Cancer or Reproductive
Toxicity
Examples
include, but are not limited to, Arsenic, Arcolein, Allyl
Alcohol, Chlorine, Nickel Carbonyl, Benzene, Beryllium, Hexavalent
Chromium Compounds, Ethylene Oxide, Methylene Chloride, Formaldehyde and
Dimethyl Mercury.
Any
questions or concerns related to the Highly Toxic and Carcinogenic
Material Program should be addressed to the Departmental Chemical Hygiene
Officer or to Jane J. Frank at
831-2103.
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