The Center for Translational Cancer Research (CTCR) at the University of Delaware

2007

Expression and Activation of avb3 Integrins by SDF-1/CXC12 Increases the Aggressiveness of Prostate Cancer Cells (The Prostate 67: 61-73). Yan-Xi Sun, Ming Fang, Jianhua Wang, Carlton R. Cooper, Kenneth J. Pienta, and Russell S. Taichman (2007).
Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model. (J Cell Physiol. 2007 May 10; [Epub ahead of print]). Degraff DJ, Malik M, Chen Q, Miyako K, Rejto L, Aguiar AA, Bancroft DR, Cohen P, Sikes RA. Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Newark, Deleware.
Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells. (Cancer Res. 2007 Apr 15;67(8):3663-72.) Deeble PD, Cox ME, Frierson HF, Sikes RA, Palmer JB, Davidson RJ, Casarez EV, Amorino GP, Parsons SJ. Department of Microbiology and Cancer Center, University of Virginia Health System, Charlottesville, VA 22908, USA.
Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix. (Int J Oncol. 2007 Apr;30(4):899-904.) Barwe SP, Maul RS, Christiansen JJ, Anilkumar G, Cooper CR, Kohn DB, Rajasekaran AK. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Coculture with Prostate Cancer Cells Alters Endoglin Expression and Attenuates Transforming Growth Factor-{beta} Signaling in Reactive Bone Marrow Stromal Cells. (Mol Cancer Res. 2007 Jun;5(6):585-603.) O'connor JC, Farach-Carson MC, Schneider CJ, Carson DD. Department of Biological Sciences, University of Delaware, Newark, DE 19716. dcarson (at udel.edu).
Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups. (J Clin Oncol. 2007 Jun 1;25(16):2313-21.) O'dwyer PJ, Eckhardt SG, Haller DG, Tepper J, Ahnen D, Hamilton S, Benson AB, Rothenberg M, Petrelli N, Lenz HJ, Diasio R, DuBois R, Sargent D, Sloan J, Johnson CD, Comis RL, O'Connell MJ; Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups, Philadelphia, PA, USA. peter.odwyer (at uphs.upenn.edu).
Using adult learning theory concepts to address barriers to cancer genetic risk assessment in the african american community. (J Genet Couns. 2007 Jun;16(3):279-88. Epub 2007 May 1.) Kendall J, Kendall C, Ali-Khan Catts Z, Radford C, Dasch K. Helen F. Graham Cancer Center, Newark, Delaware, USA.

Human and rat glioma growth, invasion, and vascularization in a novel chick embryo brain tumor model (Clin Exper Metas, 22, 225-236). Cretu, A., J.S. Fotos, B.W. Little, and D.S. Galileo (2005).
2-Microglobulin Is a Signaling and Growth-Promoting Factor for Human Prostate Cancer Bone Metastasis (Cancer Res. 2006 Sep 15;66(18):9108-16). Huang WC, Wu D, Xie Z, Zhau HE, Nomura T, Zayzafoon M, Pohl J, Hsieh CL, Weitzmann MN, Farach-Carson MC, Chung LW.
Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells. (Clin Exp Metastasis. 2006;23(1):75-86. Epub 2006 Jul 7). Muir C, Chung LW, Carson DD, Farach-Carson MC. Department of Biological Sciences, University of Delaware, Room 326 Wolf Hall, Newark, DE 19716, USA.
Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway (Molecular Cancer 2006, 5:9). Milton W. Datta, Michael J. Schlicht, Amy M DeGueme, and Andrea J. Kahler, Departments of Pathology and Urology, Emory University, Ana Maria Hernandez, Andrea Barrett and Sumana Datta, Department of Biochemistry and Biophysics, Texas A&M University, Rajiv Dhir, Department of Pathology, University of Pittsburgh Medical Center, Rajal B Shah, Department of Pathology, University of Michigan, Cindy Farach-Carson, Department of Biological Sciences, University of Delaware.
Elucidating the digital control mechanism for DNA damage repair with the p53–Mdm2 system: single cell data analysis and ensemble modelling (J. Roy. Soc. Interface. 3, 175-184, 2006). Babatunde A. Ogunnaike, Department of Chemical Engineering, University of Delaware.
In-Vitro Heating With Polyethylene Glycol Coated Fe Nanoparticles (Presented at International Magnetics Conference, San Diego, May 2006). Michael J. Bonder, Srinivasan Balakrishnan, G. Poirier, T. Moriyama, K.L. Kiick, G. C. Hadjipanayis, Magnetics Lab, University of Delaware.
Modeling Interactions Between Growth Factor and Apoptotic Signaling Pathways, Figures and Captions (Under Review by Synthetic and Systems Biology). Daniel E. Zak, Department of Chemical Engineering, University of Delaware, Boris N. Kholodenko, Department of Pathology, Thomas Jefferson University, James S. Schwaber, Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Thomas Jefferson University, and Babatunde A. Ogunnaike, Department of Chemical Engineering, University of Delaware.
Stimulation of glioma and breast cancer cell motility by proteolysis and release of the L1 neural cell recognition molecule (American Association for Cancer Research Presentation, April 2006). Shalini Adla, Murali K. Temburni, Vivek P. Patel, Muhua Yang, Errin Lagow, Alexandra Cretu, Jing Tian, Philip Kudish, Deni S. Galileo. Department of Biological Sciences, University of Delaware.
Gene expression in the LNCaP human prostate cancer progression model: Progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo (Cancer Lett. 2006 Feb 21; [Epub ahead of print]). Chen Q, Watson JT, Marengo SR, Decker KS, Coleman I, Nelson PS, Sikes RA.

2005

A Polysaccharide-Poly(ethylene glycol) Star Copolymer as a Scaffold for the Production of Bioactive Hydrogels (Biomacromolecules 2005, 6, 1921-1930). N. Yamaguchi and K. L. Kiick.
Rheological Characterization of Polysaccharide-Poly(ethylene glycol) Star Copolymer Hydrogels (Biomacromolecules 2005, 6, 1931-1940). N. Yamaguchi, B-S. Chae, L. Zhang, K. L. Kiick, K.L. and E. M. Furst.
Computational modeling reveals molecular details of epidermal growth factor binding (BioMed Central Cell Biology Research Article, November 2005). Kapil Mayawala, Dionisios G. Vlachos and Jeremy S. Edwards. Department of Chemical Engineering, University of Delaware, and Molecular Genetics and Microbiology, Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, and Chemical and Nuclear Engineering, University of New
Mexico.
Scratching below the Surface: Wound Healing and Alanine Mutagenesis Provide Unique Insights into Interactions between Eristostatin, Platelets and Melanoma Cells (2005). Mary Ann McLane, Xiaoming Zhang, Jing Tian, Claire Zelinskas, Apoorva Srivastava, Brett Hensley, Carrie Paquette-Straub, Department of Medical Technology, University of Delaware.