HHMI 
Undergraduate Research Scholars
Winter 2001
The following ten students were selected to be HHMI Research Scholars for the Winter 2001.
 
Eugene Antipov, Chemical Engineering Laura Maliszewski, Biotechnology Jennifer Rutan, Biology
Eric Evans, Biology Kate O'Reilly, Biochemistry Amanda Sheldon, Biology
Jacob LaPorte, Biochemistry Jaimie Robinson, Biochemistry Laura Tolen, Biochemistry
Michelle Denise Lazarus, Biology



 
Scholar:  Eugene Antipov

Major:  Chemical Engineering
Research Mentor:  Junghuei Chen, Department of Chemistry and Biochemistry
Project Title:  DNA Computing: The Max Problem with a Genetic Algorithm
Publications: E. Antipov, H. Bi, D. H. Wood, and J. Chen. “Implementation of Genetic Algorithms Using DNA Molecules” in preparation (2001).
        D. H. Wood. J. Chen, E. Antipov, B. Lemieux, W. Cedeno “ A Design for DNA
Computation of OneMax Problem”. Special issue on Biomolecular Approaches to
Soft Computing. Soft Computing 5, 19-24 (2001).
        J. Chen, E. Antipov, B. Lemieux, W. Cedeno, and D. H. Wood. “In vitro Selection
for a Max 1s DNA Genetic Algorithm” D. K. Gifford & E. Winfree (eds.) in press
DNA based Computer V , pp 23-39. (1999).
        D. H. Wood, E. Antipov, B. Lemieux, W. Cedeno, and J. Chen. “A DNA
Implementation of the Max 1s Problem ” in W. Banzhaf, A. Eiben, M. Garzon, V.
Honavar, M. Jakiela, and R. E. Smith (eds.) GECCO-99: Proceedings of the
Genetic and Evolutionary Computation Conference pp1835-1842 (Morgan
Kaufman, San Francisco) (1999).
        J. Chen, E. Antipov, B. Lemieux, W. Cedeno, and D. H. Wood. “ DNA Computing
Implementing Genetic Algorithms” in L. Landweber, E. Winfree, R. Lipton, and S.
Freeland (eds.) Proceedings of DIMACS Workshop on Evolution as
Computation, pp 39-49 (Piscataway, NJ) (1999).

Now:  Graduate Student in Biochemical Engineering at MIT.


 
Scholar:  Eric Evans

Major:  Biology
Research Mentor:  Patricia DeLeon, Department of Biological Sciences .

Project Title: Recombination Suppression in Spam 1

Awards and Honors: Phi Beta Kappa Clift and DeArmond Award, Phi
Kappa Phi, Phi Beta Kappa, B.S. Degree with Distinction 

Now: Graduate Student in Genetics at Stanford University on an NSF Fellowship.


 
Scholar:  Jacob LaPorte

Major:  Biochemistry
Research Mentor:  Junghuei Chen, Department of Chemistry and Biochemistry
Project Title:  Elucidating the Role of DNA Aggegates in the Homologous Recombination Strand Exchange  Reaction
Honors and Awards: Elected to Mortar Board
Publications: Zhaoquin Zhang, Dennis Yoon, Jacob R. LaPorte, and Junghuei Chen, Appropriate Initiation of Strand Exchange Reaction Promoted by RecA Protein Requires ATP Hydrolysis. (submitted 2000)
Now: Graduate School in Chemistry working in the Myers group at Harvard University on an HHMI Predoctoral Fellowship.


 
Scholar: Michelle Denise Lazarus

Major: Biology

Research Mentor: Gary Laverty, Biology

Project Title: Ammonia Transport in Avian Proximal Tubules

After Graduation: Doctoral program in Cell Biology at Thomas Jefferson
Medical College


 
Scholar: Laura Maliszewski

Major:  Biotechnology
Research Mentor:  Allan Shapiro, Department of Plant and Soil Science
Project Title: A Screen for Mutants give Programmed Cell Death in
Arabidopsis despite Chemical Inhibition of Nitric Oxide Synthase
Abstracts: Worley, C.K., Maliszewski, L.E., Hubner, J.H. and Shapiro, A. D., "Genetic Screen to Identify Arabidopsis Mutants Which Overcome a Nitric Oxide Synthase Inhibitor Block of the Hypersensitive Response" 11th International Conference on Arabidopsis Research, Madison, WI, 2000. 

Worley, C.K., Maliszewski, L.E., Hubner, J.H., Farnworth, B., Yang, H.-Y. and Shapiro, A. D., "hdn (HR Despite NOS inhibitor) Mutants Identify Multiple Controls over Arabidopsis Programmed Cell Death" 12th International Conference on Arabidopsis Research, Madison, WI, 2001 and at 10th International Congress on Molecular Plant-Microbe Interactions, Madison, WI, 2001. 

Now: Laura is a graduate student in Virology at Harvard Medical School working in the laboratory of  Prof. Judy Lieberman.


 
Scholar:  Kathryn O'Reilly  <>Major:  Biochemistry and French
Research Mentor:  John Koh, Department of Chemistry and Biochemistry
Project Title:  Redirecting Novel Transcription Regulators to New Cellular Targets
Presentation: Second Place Biochemistry Division, 64th Annual Intercollegiate Student Chemists' Conference, Bloomsburg University, 15 April 2000.
Honors and Awards: Kevin Beale Award for outstanding CHEM/BIOCHEM freshman, Phi Beta Kappa Clift and DeArmond Award for an outstanding freshman,  Phi Kappa Phi, Phi Beta Kappa, Phi Delta Pi (French Honor Society), Alpha Lambda Delta, Advanced Honors Certificate, American Chemical Society Award to the outstanding junior in chemistry or biochemistry. HHMI Undergraduate Reseach Scholar.
Publications: Hai Fen Ye, John T. Koh* and Kathryn E. O'Reilly, A subtype-selective thyromimetic designed to bind a mutant thyroid hormone receptor implicated in resistance to thyroid hormone (RTH)., J. Am. Chem. Soc., 2001, 123, 1521-1522.  (featured in C&E News)

Kristian H. Link, Federico G. Cruz, Hai-Fen Ye,  Kathryn E. O'Reilly and John T. Koh (2004) Photo-caged agonists of the nuclear receptors RARg and TRb provide unique time-dependent gene expression profiles for light-activated gene patterning. Bioorganic & Medicinal Chemistry 12, 5949-5959.

Now: MD-PhD Program at Cornell Medical School


 
Scholar:  Jaimie Robinson

Major:   Biochemistry
Research Mentor:  Eugene Mueller, Department of Chemistry and Biochemistry
Project Title:  Site-Specific Incorporation of 4-thiouridine into RNA
Abstract: Jamie S. Robinson and Eugene G. Mueller, Will introduction of an E.coli gene lead to 4-thiouridine in yeast? ASBMB Meeting, Orlando, FL. April 2001.


 
Scholar:  Jennifer Rutan

Major:  Biotechnology/History
Research Mentor:  Robert Hodson. Department of Biological Sciences
Project Title:   Characterization of 38kD Apolipoprotein DNA in the Turtle, Pseudemeyes scripta.
Honors and Awards: Elected to Mortar Board
Abstract: Jennifer Rutan, Michael Usher, Matthew Russell, Robin Davis, Shui Quig Ye, Gregory Stephens, Robert Hodson, and David Usher. Conservation of the Apolipoprotein AI-CIII Linkage Group in Reptiles. ASBMB Meetings, Orlando, FL. April 2001.

Now: Graduate student in Microbiology and Immunology at the University of North Carolina.


 
Scholar: Amanda Sheldon

Majors: Biology  and Psychology Minor: German
Research Mentor: Gary Laverty, Biology
Project Title: Localizing the Cystic Fibrosis Transmembrane Regulator in Avian Renal Proximal Tubules

Now: Graduate student in Neuropharmacology in Michael Robinson's group at the University of Pennsylvania


 
Scholar: Laura Tolen

Major: Biochemistry
Research Mentor: Hal White, Chemistry and Biochemistry
Project Title: Induction of Autoimmunity to Riboflavin-Binding Protein in Chickens.
Presentations: 65th Annual Intercollegiate Student Chemists Conference, Goucher College, 21 April 2001 
Honors and Awards: Quaesita Drake Scholarship,  Phi Beta Kappa, Phi Kappa Phi 
Activities: President, American Chemistry Society Student Affiliate Chapter 
Now: Doctoral Pharmacy Program,  University of Maryland (Completed)
 


Return to HHMI Undergraduate Research Scholars Page, University of Delaware HHMI Home Page
Created 8 December 2000, Last up-dated 29 October  2007 by Hal White [halwhite at udel.edu]
Copyright 2000, 2001, Harold B. White, Department of Chemistry and Biochemistry, University of Delaware