Tentative Schedule - Spring 2002 |
Meeting
Time and Place: Section 10 meets 3:30 to 4:45 PM Tuesdays
and Thursdays in 004 Drake Laboratory. Section 11 meets 9:30 to 10:45 AM
Tuesdays and Thursdays in 205 Brown Laboratory. Because morning and evening
lectures will be presented by the same professor and because there will
be common hourly and final examinations for both sections, students may
attend either or both lectures providing seats are available in the small
lecture room (004 QDH). The first half of the course (through March 21)
will be taught by Prof. Hal White
and the second half (starting March 26) by Prof.
Junghuei Chen. Text chapters and sections in parentheses refer to Garrett
and Grisham's, Biochemistry. Copies of the overheads
used by Dr. Chen will be on reserve in the Chemistry Library in Brown Laboratory
after Spring Break.
Tuesdays 9:30-10:45 AM & 3:30-4:45 PM | Thursdays 9:30-10:45 AM & 3:30-4:45 PM |
February 5
Introduction and Review of Metabolic Principles (Chapter 18.1-18.3) |
February 7
Glycogen Synthesis and Degradation (Chapter 23.3 - 23.5) Lactose Metabolism |
February 12
Pentose Phosphate Pathway (Chapter 23.6) NAD vs NADP in redox reactions Introduction to Fatty Acid structure and nomenclature Problem Set 1 due |
February 14
Oxidation of Odd-Chain Length and Unsaturated Fatty Acids (Chapter 8) Biosynthesis of Lipids (Chapter 25) Propionyl CoA Metabolism and B12 Glycerides Membranes & Selected Topics
|
February 19
Ketone Body Metabolism (Chapter 24.3-24.6) Citrate-pyruvate Cycle Comparison of Fatty Acid Synthesis and Degradation Problem Set 2 due |
February 21
Lipid Metabolism cont.
|
February 26
Principle of self organization Lipid Membranes Problem Set 3 due |
February 28
Nitrogen Acquisition and Excretion (Chapter 26) Amino Acid Metabolism |
March 5
Amino Acid Metabolism cont. (Chapter 26) Problem Set 4 due |
March 7
Amino Acid Metabolism cont. (Chapter 26) First Hour Exam Saturday March 9, 10 AM - noon in 205 Brown Laboratory. |
March 12
Integration of Energy Metabolism, Starvation |
March 14
Integration of Energy Metabolism, Athletic Performance |
March 19
Overview of Nucleotide Metabolism (Chapters 11 & 27) |
March 21
Introduction to Molecular Biology |
March 26 (Dr. Chen begins lecturing)
Structure and Function of DNA, History of the experiments showing DNA is the Genetic material. |
March 28
Properties of DNA, Secondary structure, Supercoiling and linking numbers |
April 3
SPRING BREAK |
April 5
SPRING BREAK |
April 9
Topoisomerases, DNA packing, Chromosome structure. |
April 11
DNA replication in prokaryotes and eukaryotes, Central Dogma |
April 16
Primosomes and Replisomes, DNA polymersaes, Mechanism of replication |
April 18
Eukaryotic replication, "Reverse transcriptase," Mutation and DNA repair |
April 23
DNA repair continued, Recombination and its enzymology. |
April 25
Recombination continued, Immunoglobulin somatic recombination, Lambda phage, Transposons. |
April 30
Transcription, RNA Polymerase, Transcription Regulation in prokaryotes, Lac operon. |
May 2
Transcription factors and termination in eukaryotes, RNA Processing, Catabolite activation Second Hour Exam based on Dr. Chen's lectures on Saturday, May 4 from 10 - noon in 101 Brown Laboratory |
May 7
Translation |
May 9
Translation continued |
May 14
Recombinant DNA methodology |
Final Comprehensive
Examination
Three hour examination scheduled during Finals Week. |