Tentative Schedule - Spring 2000
|
Tentative Schedule - Spring 2000 |
Meeting
Time and Place: Section 10 meets 9:30 to 10:45 AM Tuesdays and
Thursdays in 219 Gore Hall. Section 11 meets 7 to 8:15 PM Tuesdays and
Thursdays in 210 Brown Laboratory. Because morning and evening lectures
will be presented by the same professor and because there will be common
hourly and final examinations for both sections, students may attend either
or both lectures. The first half of the course will be taught by Prof.
Hal White and the second half by Prof.
Junghuei Chen. Text chapters and sections in parentheses refer to Garrett
and Grisham's, Biochemistry. Copies of the overheads
used by Dr. Chen are on reserve in the Chemistry Library in Brown Laboratory.
| Tuesdays 9:30-10:45 AM & 7:00-8:15 PM | Thursdays 9:30-10:45 AM & 7:00-8:15 PM |
| February 8
Introduction and Review of Metabolic Principles (Chapter 18.1-18.3) |
February 10
Glycogen Synthesis and Degradation
|
| February 15
Oxidation of Odd-Chain Length and Unsaturated Fatty Acids, Lipid Structure (Chapter 8) Biosynthesis of Lipids (Chapter 25) Problem Set 1 due |
February 17
Ketone Body Formation (Chapter 24.3-24.6) Biosynthesis of Lipids cont. (Chapter 25) Membranes & Selected Topics (Chapters 9 & 10) |
| February 22
Lipid Metabolism and Membranes cont. (Chapters 9, 10, and 25) Problem Set 2 due |
February 24
Lipid Metabolism and Membranes cont. (Chapters 9, 10, & 25) |
| February 29
Nitrogen Acquisition and Excretion (Chapter 26) Problem Set 3 due |
March 2
Amino Acid Metabolism (Chapter 26) |
| March 7
Amino Acid Metabolism cont. (Chapter 26) Problem Set 4 due |
March 9
Amino Acid Metabolism cont. (Chapter 26) |
| March 14
Integration of Metabolism and Review for Midterm Examination |
March 16
Overview of Nucleotide Metabolism (Chapters 11 & 27) (Midterm Examination Saturday March 18, 10 AM - noon in 101 Brown Laboratory.) |
| March 21
Introduction to Molecular Biology |
March 23
No class in lieu of the out-of-class midterm examination on March 18 |
| March 28 SPRING BREAK | March 30 SPRING BREAK |
| April 4
Structure and Function of DNA, History of the experiments showing DNA is the Genetic material. |
April 6
Properties of DNA, Secondary structure, Supercoiling and linking numbers |
| April 11
Topoisomerases, DNA packing, Chromosome structure. |
April 13
DNA replication in prokaryotes and eukaryotes, Central Dogma |
| April 18
Primosomes and Replisomes, DNA polymersaes, Mechanism of replication |
April 20
Eukaryotic replication, "Reverse transcriptase," Mutation and DNA repair |
| April 25
DNA epair continued, Recombination and its enzymology. |
April 27
Recombination continued, Immunoglobulin somatic recombination, Lambda phage, Transposons. |
| May 2
Transcription, RNA Polymerase, Transcription Regulation in prokaryotes, Lac operon. |
May 4
Transcription factors and termination in eukaryotes, RNA Processing, Catabolite activation |
| May 9
Translation |
May 11
Translation continued Second Hour Exam based on Dr. Chen's lectures on Saturday, May 13 from 10 - noon in 101 Brown Laboratory |
| May 16
Recombinant DNA methodology |
Friday May 26
Final Comprehensive Examination 3:30 - 6:30 in 130 Sharp Laboratory |