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INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2014 |
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INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2014 |
The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.
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| August 27 Intro. and Review of Metabolic Principles |
August 29 Form Groups, Group work on metabolic reactions involving pyruvate. |
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| September 1 Labor Day - Holiday |
September 3 ATP and Bioenergetics Energy Charge, and Adenylate Metabolism. |
September 5 Inborn Errors of Metabolism - Assignment due Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes |
| September 8 Adenylate Kinase and Adenylate Energy Charge Aspects of Metabolic regulation by Adenylates Homing in on Catabolism of Lipid, Carbohydrates, and Proteins |
September 10 Lactose structure and metabolism Pentose Phosphate Pathway NAD vs NADP in Redox Reactions |
September 12
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| September 15 Life Without Oxygen problem, 2a, 2b, Go over Homework Problem set 2 |
September 17 Life Without Oxygen problem, 3, Summary Are you what you eat? Page 1 Read text chapter on Photosynthesis for Friday Calvin-Benson Cycle Intermediates-cutout |
September 19 Calvin Cycle Are you what you eat? Pages 2a & b |
| September 22 Are you what you eat? Page 3 & 4 |
September 24 Are you what you eat? Page 5 |
September 26 Concluding Discussions, Summary |
| September 29 Group quiz on Glycolysis and Photosynthesis |
October 1 Intro to Fatty Acid Structure and Nomenclature Fatty acid oxidation Fatty Acid Synthesis vs Degradation Coenzyme A structure and function |
October 3 Ketone Body Metabolism Propionyl CoA Metabolism Coenzyme B12 Lipid Metabolism - Problems due |
| October 6 Citrate-pyruvate Cycle Glyceride Metabolism |
October 8 Steroid and Isoprenoid Biosynthesis Overview of Isoprenoid metabolism HMG-CoA and IPP synthesis |
October 10 Rxns of HMGCoA - Problem due Wrap up lipid metabolism The Nitrogen Cycle Intorduction to nitrogen fixation |
| October 13 Conceptual Class Activity on Modular assembly and self assembly in biosynthesis |
October 15 Nitrogenase Nitrate and Nitrite Reduction Molybdopterin Intro. Amino Acid Metabolism Nitrogen Acquisition and Excretion |
October
17 Lysine Biosynthesis - Problem due Ammonium entry into metabolism Glutamine Synthetase and its Regulation Pyridoxal Phosphate (PLP) |
| October 20 Glutamate Family of Amino Acids Synthesis of Proline from Glutamate Synthesis of Arginine from Glutamate via Ornithine |
October 22 Flux in Metabolism Oxaloacetate Family of Amino Acids Regulation of Branched Biosynthetic Pathways |
October 24 Biosynthesis of Essential Amino Acids - due Generation of Formyl and Methyl Groups- Folate Metabolism Urea Cycle Amino Acid Catabolism |
| October 27 Creatine Creates Controversy p1-5 |
October 29 Sick Kids with an Unusual Organic Aciduria p1, p2, Summary |
October 31 Human Starvation Metabolic Limits of Human Performance |
| November
3 Midterm Exam, (examinations for the past 10 years posted on course home page.) 8:00 am - 10 am |
November 5 Review of Examination |
November 7 Plant vs Animals in the Dining Hall. Page 1 |
| November 10 Plant vs Animals in the Dining Hall. Page 2 |
November 12 Plant vs Animals in the Dining Hall Page 3 |
November 14 Plant vs Animals in the Dining Hall. Page 4, Page 5, and Summary |
| November 17 Begin Final Group Project |
November 19 Group Project |
November 21 Group Project |
| November 24 Group Project |
November 26 Thanksgiving Break |
November 28 Thanksgiving Break |
| December 1 Group Project due Group Project Preparation |
December 3 Group Project Presentations On-line course evaluations due |
Review session Tuesday, December 9, 2014, 2:00-4:00 PM in
205 Brown Lab. Final Exam (examinations for the past 10 years posted on course home page.) Wednesday, December 10, 2014, 3:30-6:30 PM in 205 Brown Lab. |
