INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2013 |
The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.
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August 28 Intro. and Review of Metabolic Principles |
August 30 ATP and Bioenergetics Energy Charge, and Adenylate Metabolism. |
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September 2 Labor Day - Holiday |
September 4 Form Groups, Group work on metabolic reactions involving pyruvate. |
September 6 Inborn Errors of Metabolism - Assignment due Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes |
September 9 Lactose structure and metabolism Pentose Phosphate Pathway (oxidative branch) |
September 11 Pentose Phosphate Pathway (non-oxidative branch) NAD vs NADP in Redox Reactions |
September 13
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September 16 Go over Homework Problem set 2 Wrap up Life Without Oxygen problem, 3, Summary |
September 18 Are you what you eat? Page 1 Read text chapter on Photosynthesis for Friday Calvin-Benson Cycle Intermediates-cutout Calvin Cycle |
September 20 Are you what you eat? Page 2 |
September 23 Are you what you eat? Page 3 & 4 |
September 25 Are you what you eat? Page 5 |
September 27 Concluding Discussions, Summary |
September 30 Group quiz on Glycolysis and Photosynthesis |
October 2 Intro to Fatty Acid Structure and Nomenclature Fatty acid oxidation Fatty Acid Synthesis vs Degradation Coenzyme A structure and function |
October 4 Ketone Body Metabolism Propionyl CoA Metabolism Coenzyme B12 Lipid Metabolism - Problems due |
October 7 Citrate-pyruvate Cycle Glyceride Metabolism |
October 9 Steroid and Isoprenoid Biosynthesis Overview of Isoprenoid metabolism HMG-CoA and IPP synthesis |
October 11 Rxns of HMGCoA - Problem due Wrap up lipid metabolism The Nitrogen Cycle Intorduction to nitrogen fixation |
October 14 Conceptual Class Activity on Modular assembly and self assembly in biosynthesis |
October 16 Nitrogenase Nitrate and Nitrite Reduction Molybdopterin Intro. Amino Acid Metabolism Nitrogen Acquisition and Excretion |
October
18 Lysine Biosynthesis - Problem due Ammonium entry into metabolism Glutamine Synthetase and its Regulation Pyridoxal Phosphate (PLP) |
October 21 Glutamate Family of Amino Acids Synthesis of Proline from Glutamate Synthesis of Arginine from Glutamate via Ornithine |
October 23 Flux in Metabolism Oxaloacetate Family of Amino Acids Regulation of Branched Biosynthetic Pathways |
October 25 Biosynthesis of Essential Amino Acids - due Generation of Formyl and Methyl Groups- Folate Metabolism Urea Cycle Amino Acid Catabolism |
October 28 Creatine Creates Controversy p1-5 |
October 30 Sick Kids with an Unusual Organic Aciduria p1, p2, Summary |
November 1 Human Starvation Metabolic Limits of Human Performance |
November
4 Midterm Exam Review session. |
November 6 Midterm Exam 8:00 am - 10 am |
November 8 Plant vs Animals in the Dining Hall. Page 1 |
November 11 Plant vs Animals in the Dining Hall. Page 2 |
November 13 Plant vs Animals in the Dining Hall Page 3 |
November 15 Plant vs Animals in the Dining Hall. Page 4, Page 5, and Summary |
November 18 Begin Final Group Project |
November 20 Group Project |
November 22 Group Project |
November 25 Group Project |
November 27 Thanksgiving Break |
November 29 Thanksgiving Break |
December 2 Group Project due Group Project Presentations |
December 4 Group Project Presentations On-line course evaluations due |
Final
Exam 7-10 PM Monday, 9 December, in 206 Brown Lab |