CHEM-643
INTERMEDIARY METABOLISM
Tentative Schedule
FALL SEMESTER 2011

The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.

Monday
Wednesday
Friday 

August 31
Intro. and Review of Metabolic Principles
Canceled due to Hurricane Irene
September 2
ATP and Bioenergetics   
Energy Charge, and Adenylate Metabolism.
September 5
Labor Day - Holiday
September 7
Form Groups, Group work on metabolic reactions involving pyruvate.
September 9
Inborn Errors of Metabolism - Assignment due
Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes
September 12
Lactose structure and metabolism
Pentose Phosphate Pathway  (oxidative branch)
September 14
Pentose Phosphate Pathway  (non-oxidative branch) 
NAD vs NADP in Redox Reactions

September 16
Review of Carbohydrate Metabolism
- Problems due

Life Without Oxygen problem for groups in class
Page 1, 2, 2a, 2b

September 19
Go over Homework Problem set 2
Wrap up Life Without Oxygen problem, 3, 4, Summary
September 21
Are you what you eat?  Page 1
Read text chapter on Photosynthesis for Friday
Calvin Cycle
September 23
Are you what you eat? Page 2

September 26
Are you what you eat? Page 3 & 4
September 28
Are you what you eat? Page 5
September 30
Concluding Discussions
Summary
October 3
Group quiz on Glycolysis and Photosynthesis

October 5
Intro to Fatty Acid Structure and Nomenclature
Fatty acid oxidation
Fatty Acid Synthesis vs Degradation
Coenzyme A structure and function
October 9
Ketone Body Metabolism
Propionyl CoA Metabolism
Coenzyme B12
Lipid Metabolism - Problems  due
October 10
Citrate-pyruvate Cycle
Glyceride Metabolism
October 12
Steroid and Isoprenoid Biosynthesis
Overview of Isoprenoid metabolism
HMG-CoA and IPP synthesis
October 14
Rxns of HMGCoA - Problem due
Wrap up lipid metabolism
The Nitrogen Cycle
Intorduction to nitrogen fixation
October 17
Conceptual Class Activity on Modular assembly and self assembly in biosynthesis
October 19
Nitrogenase
Nitrate and Nitrite Reduction
Molybdopterin 
Intro. Amino Acid Metabolism
Nitrogen Acquisition and Excretion
October 21
Lysine Biosynthesis - Problem due
Ammonium entry into metabolism
Glutamine Synthetase and its Regulation
Pyridoxal Phosphate (PLP)
October 24
Glutamate Family of Amino Acids
Synthesis of Proline from Glutamate
Synthesis of Arginine from Glutamate via Ornithine 
October 26
Flux in Metabolism
Oxaloacetate Family of Amino Acids
Regulation of Branched Biosynthetic Pathways
October 28
Biosynthesis of Essential Amino Acids - due
Generation of Formyl and Methyl Groups-
Folate Metabolism
October 31
Urea Cycle
Amino Acid Catabolism
November 2
Human Starvation
Metabolic Limits of Human Performance
November 4
Midterm Exam
8:00 am - 10 am

November 7
Plant vs Animals in the Dining Hall.  Page 1
November 9
Plant vs Animals in the Dining Hall.  Page 2
November 11
Plant vs Animals in the Dining Hall.  Page 3
November 14
Plant vs Animals in the Dining Hall.  Page 4
November 16
Plant vs Animals in the Dining Hall.
Page 5
November 18
Group quiz amino acid metabolism
Plant vs Animals in the Dining Hall.- Summary
November 21
Begin Final Group Project
November 23
Thanksgiving Break
November 25
Thanksgiving Break
November 28
Group Project
November 30
Group Project
December 2
Group Project due
December 5
Group Project Presentations
December 7
Group Project Presentations
Last Class
On-line course evaluations due
Final Exam 
Tuesday, 13 December
7-10 PM,  127 Memorial Hall

Return to Department's Home Page, CHEM-643 Home Page, CHEM-643 Syllabus, or Hal White's Home Page.
Last updated 16 November 2011 by Hal White. (halwhite at udel.edu)
Copyright 2011, Harold B. White, Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716