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INTERMEDIARY METABOLISM Schedule FALL SEMESTER 2011 |
The class meets Monday, Wednesday, and Friday from 9:05 to 9:55 AM in 205 Brown Laboratory.
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| August 31 Intro. and Review of Metabolic Principles Canceled due to Hurricane Irene |
September 2 ATP and Bioenergetics Energy Charge, and Adenylate Metabolism. |
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| September 5 Labor Day - Holiday |
September 7 Form Groups, Group work on metabolic reactions involving pyruvate. |
September 9 Inborn Errors of Metabolism - Assignment due Review of Pyruvate Pyruvate metabolism, Pyruvate dehydrogenase and its coenzymes |
| September 12 Lactose structure and metabolism Pentose Phosphate Pathway (oxidative branch) |
September 14 Pentose Phosphate Pathway (non-oxidative branch) NAD vs NADP in Redox Reactions |
September 16
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| September 19 Go over Homework Problem set 2 Wrap up Life Without Oxygen problem, 3, 4, Summary |
September 21 Are you what you eat? Page 1 Read text chapter on Photosynthesis for Friday Calvin Cycle |
September 23 Are you what you eat? Page 2 |
| September 26 Are you what you eat? Page 3 & 4 |
September 28 Are you what you eat? Page 5 |
September 30 Concluding Discussions Summary |
| October 3 Group quiz on Glycolysis and Photosynthesis |
October 5 Intro to Fatty Acid Structure and Nomenclature Fatty acid oxidation Fatty Acid Synthesis vs Degradation Coenzyme A structure and function |
October 9 Ketone Body Metabolism Propionyl CoA Metabolism Coenzyme B12 Lipid Metabolism - Problems due |
| October 10 Citrate-pyruvate Cycle Glyceride Metabolism |
October 12 Steroid and Isoprenoid Biosynthesis Overview of Isoprenoid metabolism HMG-CoA and IPP synthesis |
October 14 Rxns of HMGCoA - Problem due Wrap up lipid metabolism The Nitrogen Cycle Intorduction to nitrogen fixation |
| October 17 Conceptual Class Activity on Modular assembly and self assembly in biosynthesis |
October 19 Nitrogenase Nitrate and Nitrite Reduction Molybdopterin Intro. Amino Acid Metabolism Nitrogen Acquisition and Excretion |
October
21 Lysine Biosynthesis - Problem due Ammonium entry into metabolism Glutamine Synthetase and its Regulation Pyridoxal Phosphate (PLP) |
| October 24 Glutamate Family of Amino Acids Synthesis of Proline from Glutamate Synthesis of Arginine from Glutamate via Ornithine |
October 26 Flux in Metabolism Oxaloacetate Family of Amino Acids Regulation of Branched Biosynthetic Pathways |
October 28 Biosynthesis of Essential Amino Acids - due Generation of Formyl and Methyl Groups- Folate Metabolism |
| October 31 Urea Cycle Amino Acid Catabolism |
November 2 Human Starvation Metabolic Limits of Human Performance |
November 4 Midterm Exam 8:00 am - 10 am |
| November
7 Plant vs Animals in the Dining Hall. Page 1 |
November 9 Plant vs Animals in the Dining Hall. Page 2 |
November 11 Plant vs Animals in the Dining Hall. Page 3 |
| November 14 Plant vs Animals in the Dining Hall. Page 4 |
November 16 Plant vs Animals in the Dining Hall. Page 5 |
November 18 Group quiz amino acid metabolism Plant vs Animals in the Dining Hall.- Summary |
| November 21 Begin Final Group Project |
November 23 Thanksgiving Break |
November 25 Thanksgiving Break |
| November 28 Group Project |
November 30 Group Project |
December 2 Group Project due |
| December 5 Group Project Presentations |
December 7 Group Project Presentations Last Class On-line course evaluations due |
Final
Exam Tuesday, 13 December 7-10 PM, 127 Memorial Hall |