CHEM-527
INTRODUCTORY BIOCHEMISTRY
Tentative Schedule
FALL SEMESTER 2013

The class meets Tuesday and Thursdays from 9:30 to 10:45 AM in 206 Brown Kirkbride Hall.

The following schedule is subject to minor changes.  The order of topics follows the sequence of chapters in the textbook, Essential Biochemistry, by Pratt and Cornely.  An optional problem session will be held each week (Monday, Wed, and Thursday 7 - 9 PM in 205 Brown Lab).  There will be 15 minute quizzes at the beginning od class on Thursdays

Tuesday
Thursday 
Aug. 27 -  Introduction to the Course.
 Aug. 29 - Chapter 1   Chemical Basis of Life

Sept. 3 -  Chapter 2   Aqueous Chemistry

Challenge Problem – No Sweat for Camels

Sept. 5 -  Chapter 3   From Genes to Proteins

Challenge Problem – Finding or Relaticves
Sept. 10 - Chapter 3 continued   From Genes to Proteins

Sept. 12 – Chapter 4   Protein Structure and Function

Challenge Problem – ATCase Structure

Sept. 17 - Chapter 5   Protein Function – Hemoglobin

Challenge Problem – Hemoglobin Variants		 Sept. 19 – Chapter 6   How Enzymes Work

Sept. 24 - Chapter 7   Enzyme Kinetics and Inhibition

Challenge Problem – Proline Racemase		 Sept. 26 – First Hourly Exam     Chapters 1-7

Oct. 1 –  Chapter 8 & 9    Lipids and Membranes and Membrane Transport

Challenge Problem - Transmembrane Proteins		 Oct. 3 -   What Color is Egg White? Demonstration
Oct. 8 –  Chapter 10    Signaling Oct. 10 – POGIL Activity on Sugars
Oct. 15 – Chapter 11   Carbohydrates Oct. 17 – Chapter 12   Metabolism and Bioenergetics

Oct. 22 – Chapter 13   Glucose Metabolism

Challenge Problem – Alternative to Glycolysis

Oct. 23 - Chapter 13   Lactose Metabolism  and The Pentose Phosphate Pathway

Challenge Problem – Lysine Biosynthesis in Fungi
Oct. 29 – Chapter 14   Roles of NAD and NADP, Pyruvate Dehydrogenase, The Citric Acid Cycle Oct. 31 – Chapter 15   Chapter Electron Transport Chain

Nov. 5 - Chapter 15 & 16 Electron Transport Chain, Cytochrome c Evolution, Light Reactions of Photosynthesis

Challenge Problem – HMGCoA Metabolism

Nov. 7 -  Chapter 16 & 17   Dark Reactions of Photosynthesis & Beta oxidation of Fatty Acids

Challenge Problem - Essential Amino Acid Biosynthesis
Nov. 12 – Chapter 17   Ketone Bodies, Fatty Acid Syntheis, & Starvation in Man Nov. 14 – Second Hourly Exam   Chapters 8 - 17
Nov. 19 - Chapter 18   Nitrogen Metabolism   Nov. 21 – Amino acid biosynthesis & Introduction to Central Dogma of Molecular Biology

Nov. 26 - Nucleotide Biosynthesis

Challenge Problem – Mutational Analysis		 Nov. 28  THANKSGIVING BREAK

Dec. 3 – DNA, RNA, and Protein Synthesis

Challenge Problem – Codon Bias 		Final Exam 
3:30 - 6:30 PM Friday, 13 December in 206 Brown Laboratory
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Last updated 17 December, 2013 by Hal White. (halwhite at udel.edu)
Copyright 2013, Harold B. White, Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716