CHEM-653
Bioinorganic Chemistry
TR 8:00 am

207 BRL

Professor Charles G. Riordan
LDL 211
x1073
riordan@udel.edu
Office Hours - MF 9:00 - 10:00 am
or by appointment


Text: There are no required texts for this course.  Most of the material is taken from the current literature.  Below is a list of several texts that serve as appropriate background.

Supporting Texts: The first four entries below are available from the reserve desk at the Chemistry Library, 2nd floor Brown Laboratory.

Biological Inorganic Chemistry- Structure & Reactivity Bertini, Gray, Stiefel and Valentine, 2007, University Science Books
Inorganic Biochemistry, An Introduction J. A. Cowan, 1997, Wiley-VCH
Principles of Bioinorganic Chemistry S. J. Lippard and J. M. Berg, 1994, University Science Books
Physical Methods in Bioinorganic Chemistry L. Que, Jr., 2000, University Science Books

Bioinorganic Enzymology, Thematic Issue in Chemical Reviews, 1996, 96(7).  Holm and Solomon, Ed.
Medicinal Inorganic Chemistry, Thematic Issue in Chemical Reviews, 1999, 99(7).
  Orvig and Abrams, Ed.

Biomimetic Inorganic Chemistry, Thematic Issue in Chemical Reviews, 2004, 104(2). Holm and Solomon, Ed.
Comprehensive Coordination Chemistry II, 2003, Chapter 8 Bioinorganic Chemistry
Current Scientific Literature


Grading:
Problem Sets: 20%

Midterm Examination: 25%
Group Presentation: 25%
Final Examination: 25%

Class Participation: 5%


Learning Goals
Among the objectives of this course, it is expected that students who successfully complete the semester will be able to:

understand the various roles of metal ions in biology including native metals and the use of metals as diagnostic and therapeutic agents (1,2);

understand the relationship between metal ion properties and structural and functional roles (1);

qualitatively and quantitatively evaluate spectroscopic properties of metal complexes for understanding electronic structure and to relate structure to function (1,4);

enhance their problem-solving skills (3);

formulate independent research ideas in the field of bioinorganic chemistry (3);

critically read, analyze and present to others research from the bioinorganic chemistry literature (4,10);

participate fully, i.e. understand and ask questions, in seminars related to bioinorganic chemistry (1,4).

(Numbers reflect alignment with Department Learning Goals/Outcomes as contained at http://www.udel.edu/chem/goals/html)


Code of Conduct
All students are expected to abide by the University’s Code of Conduct regarding Academic Honesty.


Last updated: July 12, 2010