CHEM-653
Bioinorganic Chemistry
TR 8:00 am
207 BRL

Professor Charles G. Riordan
LDL 211
x1073
riordan@udel.edu
Office Hours - MF 9:00 - 10:00 am
or by appointment
 
 

Topics to be discussed:
Week 1- Introduction and overview of metals in biology  
Week 2- Choice, transport and storage of metal ions
Week 3- Metal chaperones, transporters and metalloregulatory sensors
Week 4- Electron transfer sites and long distance electron transfer
Week 5- Dioxygen - uptake and transport
Week 6- Dioxygen - activation and utilization
Week 7- Protective enzymes - SOD, catalase, peroxidase
Week 8- Nitrogenase
Week 9- Photosynthesis
Week 10- Bioorganometallic chemistry- B12 and nickel enzymes  
Week 11- Hydrogenases  
Week 12- Radical-generating enzymes; DNA-binding proteins
Week 13- Metals in medicine

 

Departmental Seminars/Colloquia of special note:
 February 27 - Inorganic - John Bercaw, CalTech
March 11 - Physical - Sarah Eaton, University of Denver
April 6 - Biochemistry Greg Petsko, Brandeis
May 8 - Inorganic – Chris Chang, UC-Berkeley