Publications from Delaware (as of May 2011)

50) Taylor, M. T.; Blackman, M. L.; Dmitrenko, O.; Fox, J. M. “Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine-trans-Cyclooctene Ligation” J. Am. Chem. Soc. 2011, ASAP

49) Selvaraj, R.; Liu, S.; Hassink, M.; Huang, C.-w.; Yap, L.-p.; Park, R.; Fox, J. M.; Li, Z.; Conti, P. S. “Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin α_vβ₃ targeted PET tracer based on a cyclic RGD peptide” Bioorganic and Medicinal Chemistry Letters 2011, ASAP.

48) Hassink, M.; Liu, X.; Fox, J. M. “Copper-catalyzed Synthesis of Allenoates from a-Substituted a -Diazoesters” Org. Lett. 2011, ASAP. PMCID in process; NIHMSID: NIHMS288587.

47) DeAngelis, A.; Shurtleff, V. W.; Dmitrenko, O.; Fox, J. M. J. Am. Chem. Soc. 2011, 133, 1650. PMCID in process; NIHMSID # 268105

46) Dong, Z.; Bai, S.; Yap, G. P. A.; Fox, J. M. “Interplay between Diamine Structure and Absolute Helicity in Ni-salen Metallofoldamers” Chem. Commun. 2011, 47, 3781-3783.

45) Li, Z.; Cai, H.; Hassink, M.; Blackman, M. L.; Brown, R. C. D.; Conti, P. S.; Fox, J. M. "Tetrazine-trans-Cyclooctene Ligation for the Rapid Construction of F-18 Labeled Probes” 2010, 46, 8043-8045.

44) Dong, Z.; Plampin, J. N. III; Yap, G. P. A.; Fox, J. M. ‘Minimalist Endgroups for Control of Absolute Helicity in Salen- and Salophen-based Metallofoldamers’ Org. Lett. 2010, 12, 4002–4005.

43) DeAngelis, A.; Boruta, D. T.; Lubin, J.-B.; Plampin, J. N. III, Fox, J. M. “The Chiral Crown Conformation in Paddlewheel Complexes” Chemical Communications 2010, 4541-4543.

42) Xie, X.; Yang, Z.; Fox, J. M. “Stereospecific synthesis of alkylidenecyclopropanes via sequential cyclopropene carbomagnesation/1,3-carbon shift" J. Org. Chem. 2010, 75, 3847–3850.

41) Fisher, L. A.; Zhang, F.; Yap, G. P. A.; Fox, J. M. “Weak absolute helicity direction in Ni–salen by trans-cyclohexane-(1R,2R)-diamine” Inorg. Chim. Acta. 2010, 364, 259-260.

40) DeAngelis, A.; Dmitrenko, O.; Yap, G. P. A.; Fox, J. M. “Chiral Crown Conformation of Rh₂(S-PTTL)₄: Enantioselective Cyclopropanation with α-Alkyl-α-diazoesters” J. Am. Chem. Soc., 2009, 131, 7230–7231

39) Tarwade, V.; Liu, X.; Yan, N.; Fox, J. M. “Directed Carbozincation Reactions of Cyclopropene Derivatives” J. Am. Chem. Soc. 2009, 131, 5382-5383.

38) DeAngelis A.; Taylor M. T.; Fox, J. M. “Unusually Reactive and Selective Carbonyl Ylides for Three-component Cycloaddition Reactions” J. Am. Chem. Soc. 2009, 131, 1101-1105.

37) Blackman, M. L.; Royzen, M.; Fox, J. M. "The Tetrazine Ligation: Fast Bioconjugation Based on Inverse-electron-demand Diels-Alder Reactivity" J. Am. Chem. Soc. 2008, 130, 13518–13519

36) Fisher, L. A.; Fox, J. M. "Studies on the Stability of Cycloprop-2-ene Carboxylate Dianions and Reactions with Electrophiles" J. Org. Chem. 2008, 73, 8474–8478.

35) Tarwade, V.; Dmitrenko, O.; Bach, R. D.; Fox, J. M. "The Curtius Rearrangement of Cyclopropyl- and Cyclopropenoyl Azides. A Combined Theoretical and Experimental Mechanistic Study” J. Org. Chem. 2008, 73, 8189–8197.

34) Pallerla, M. K.; Yap, G. P. A.; Fox, J. M. “Co-complexes Derived from Alkene Insertion to Alkyne-dicobaltpentacarbonyl Complexes: Insight into the Regioselectivity of Pauson-Khand Reactions of Cyclopropenes” J. Org. Chem. 2008 73, 6137–6141.

33) Panne, P.; DeAngelis, A.; Fox, J. M. “Rh-Catalyzed Intermolecular Cyclopropanation with α-Alkyl-α-diazoesters: Catalyst-Dependent Chemo- and Diastereoselectivity” Org Lett. 2008, ASAP

32) Yan, N.; Liu, X.; Pallerla, M.; Fox, J. M. “ Synthesis of Stable Derivatives of Cycloprop-2-ene Carboxylic Acid” J. Org. Chem. 2008, 73, 4283-4286.

31) Royzen, M.; Yap, G. P. A.; Fox, J. M. “A Photochemical Synthesis of Functionalized trans-Cyclooctenes Driven by Metal Complexation” J. Am. Chem. Soc. 2008, 130, 3760–3761.

30) DeAngelis, A.; Panne, P.; Yap, G. P. A.; Fox, J. M. “Rh-Catalyzed Formation of Dioxolanes from a-Alkyl Diazoesters: Diastereoselective Cycloadditions of Carbonyl Ylides with Selectivity over b-Hydride Elimination” J. Org. Chem. 2008, 73, 1435-1439.

29) Yan, N.; Liu, X.; Fox, J. M. “Facially Selective and Regioselective Carbometalation of Cyclopropenes by Aryl Grignard Reagents” J. Org. Chem. 2008, 73, 563-568.

28) Pallerla, M. K.; Fox, J. M. “Enantioselective Synthesis of (–)-Pentalenene” Org. Lett. 2007, 9, 5625-5628.

27) Dong, Z.; Yap, G. P. A.; Fox, J. M. “trans-Cyclohexane-1,2-diamine is a Weak Director of Absolute Helicity in Chiral Nickel-Salen Complexes” J. Am. Chem. Soc. 2007, 129, 11850-11853.

26) Panne, P.; Fox, J. M. “Rh-catalyzed Intermolecular Reactions of Alkynes with α-Diazoesters that Possess β-hydrogens: Ligand-based Control over Divergent Pathways” J. Am. Chem. Soc. 2007, 129, 22-23.

25) Dong, Z.; Liu, X.; Yap, G. P. A.; Fox, J. M. “Two-Dimensional Scaffolds for the Parallel Alignment of Rod-Shaped Conjugated Molecules” J. Org. Chem. 2007, 72, 617-625.

24) Dong, Z.; Karpowicz, R. J. Jr. (undergraduate); Bai, S.; Yap, G. P. A.; Fox, J. M. “Control of Absolute Helicity in Single-Stranded Abiotic Metallofoldamers” J. Am. Chem. Soc. 2006, 128,14242-14243.

23) Zhang, F.; Fox, J. M. “Synthesis of Cyclopropene a-Amino Acids by Enantioselective Desymmetrization” Organic Letters 2006, 8, 2965-2968.

22) Liu, X.; Fox, J. M. “Enantioselective, Facially Selective Carbomagnesation of Cyclopropenes” J. Am. Chem. Soc. 2006, 128, 5600-5601.

21) Yang, Z.; Xie, X.; Fox, J. M. “Diastereoselective Synthesis of Methylenecyclopropanes from Chiral Cyclopropene Derivatives” Angew. Chem. Int. Edit. 2006, 45, 3960-3962.

20) Pallerla, M. K.; Fox, J. M. “Diastereoselective Intermolecular Pauson Khand Reactions of Chiral Cyclopropenes” Organic Letters 2005, 7, 3593-3596.

19) Zhang, F.; Bai, S.; Yap, G. P. A.; Tarwade, V.; Fox, J. M. “Abiotic Metallofoldamers as Electrochemically Responsive Molecules” J. Am. Chem. Soc. 2005, 127, 10590-10599.

18) Fox, J. M.; Yan, N. “Metal Mediated and Catalyzed Nucleophilic Additions to Cyclopropenes” Current Organic Chemistry 2005, 9, 719-732. (Invited Contribution).

17) Liao, L.-a.; Yan, N.; Fox, J. M. “The Dianion Approach to Chiral Cyclopropene Carboxylic Acids” Organic Letters 2004, 6, 4937-4939.

16) Fox, J. M.; Dmintrenko, O.; Liao, L.-a.; Bach. R. D. “Computational Studies of Nucleophilic Substitution at Carbonyl Carbon: Applications to Organic Synthesis” J. Org. Chem. 2004, 69, 7317-7328.

15) Stone, M. T.; Fox, J. M.; Moore, J. S. “A Helicene-Containing Foldamer Displaying Highly Solvent Dependent CD Spectra” Org. Lett. 2004, 6, 3317-3320.

14) Liao, L.-a.; Zhang. F.; Dmintrenko, O.; Bach, R. D.; Fox, J. M. “A Reactivity/Affinity Switch for Parallel Kinetic Resolution: a-Amino Acid Quasienantiomers and the Resolution of Cyclopropene Carboxylic Acids” J. Am. Chem. Soc. 2004, 126, 4490-4491.

13) Liao, L.-a.; Zhang, F.; Yan, N.; Golen, J. A.; Fox, J. M. “An Efficient and General Method for Resolving Cyclopropene Carboxylic Acids” Tetrahedron 2004, 1803-1816.

12) Liao, L.-a.; Fox, J. M. "A Copper-catalyzed Method for the Facially Selective Addition of Grignard Reagents to Cyclopropenes" J. Am. Chem. Soc. 2002, 124, 14322–14323.

Publications from Postdoctoral Research

11) Kaye, S. (undergraduate mentored by Fox); Fox, J. M.; Hicks, F. A.; Buchwald, S. L. "The Use of Catalytic Amounts of CuCl and Other Improvements in the Benzyne Route to Biphenyl-Based Ligands" Adv. Synth. Catal. 2001, 343, 789.

10) Chieffi, A.; Kamikawa, K.; Åhman, J.; Fox, J. M. "Catalytic Asymmetric Vinylation of Ketone Enolates" Org. Lett. 2001, 3, 1897-1900.

9) Tomori, H.; Fox, J. M.; Buchwald, S. L. "An Improved Synthesis of Functionalized Biphenyl-Based Phosphine Ligands" J. Org. Chem. 2000, 65, 5334.

8) Fox, J. M.; Huang, X.; Chieffi, A.; Buchwald, S. L. "Highly Active and Selective Catalysts for the Formation of a-Aryl Ketones" J. Am. Chem. Soc. 2000, 122, 1360.

7) Buchwald, S. L.; Fox, J. M. "Recent Progress in the Suzuki Reactions of Aryl Chlorides" Strem Chemiker 2000 Vol. XVIII No. 1.

Publications from Graduate Studies

6) Fox, J. M.; Katz, T. J.; Van Elschocht, S.; Verbiest, T.; Kauranen, M.; Persoons, A.; Thongpanchang, T.; Krauss, T.; Brus, L. "Synthesis, Self-Assembly, and Nonlinear Optical Properties of Conjugated Helical Metal Phthalocyanine Derivatives" J. Am. Chem. Soc. 1999, 121, 3454.

5) Fox, J. M.; Katz, T. J. "Conversion of a [6]Helicene into an [8]Helicene and a Helical 1,10-Phenanthroline Ligand" J. Org. Chem. 1999, 64, 302.

4) Fox, J. M.; Goldberg, N. R. (undergraduate mentored by Fox); Katz, T. J. "Efficient Synthesis of Functionalized [7]Helicenes" J. Org. Chem. 1998, 63, 7456.

3) Fox, J. M.; Lin, D. (undergraduate mentored by Fox); Itagaki, Y.; Fujita, T. "Synthesis of Conjugated Helical Acetylene-Bridged Polymers and Cyclophanes" J. Org. Chem. 1998, 63, 2031.

2) Katz, T. J.; Liu, L.; Willmore, N. D.; Fox, J. M.; Rheingold, A. L.; Shi, S.; Nuckolls, C.; Rickman, B. H. "An Efficient Synthesis of Functionalized Helicenes" J. Am. Chem. Soc. 1997, 119, 10054.

Publication from Undergraduate Studies

1) Fox, J. M.; Scacheri Gillen, J. E.; Jones, K. J. L.; Jones, M., Jr.; Shevlin, P. B.; Armstrong, B.; Sztyrbicka, R. "The Phenylcarbene Rearrangement as a Source of Real Carbenes" Tetrahedron Lett. 1992, 33, 5021.