UNIVERSITY OF DELAWARE GRADUATE PROGRAM AT THE

chemistry/biology interface

The University of Delaware offers a multidisciplinary graduate program at the interface between chemistry and biology, funded by NIH. The program involves faculty from six academic units and allows students to obtain a Ph.D. degree in either Chemistry and Biochemistry, in Chemical Engineering or in Biological Sciences. Research disciplines include: biochemistry, biochemical engineering, bioorganic chemistry, molecular biology, cell biology, virology, bioanalytical chemistry, structural biology, bioinorganic chemistry, materials science and plant biochemistry. The program features: laboratory rotations to introduce students to diverse research areas; graduate courses that can be selected from six departments; a course on scientific integrity and ethical principles in research; a multidisciplinary seminar; and an intense research experience culminating in the submission of a Ph.D. dissertation.
CBI Collage

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CBI Goals

Our goal is to provide a multidisciplinary education for a talented group of students to enable them to apply the mechanistic, synthetic and analytical approaches of chemistry to important biological problems. Students may obtain a Ph.D. degree in either Chemistry and Biochemistry, in Chemical Engineering, or in Biological Sciences.

 

CBI OPPORTUNITY
  • An intensive research experience in the laboratory of any faculty member of the Chemistry-Biology Interface Program leads to a research dissertation.
  • Multidisciplinary Chemistry-Biology Interface Seminar, attended by students and faculty in the Chemistry-Biology Interface Program, featuring student and faculty presentations, as well as seminars by outside speakers from academia and industry.
  • Ph.D. Advisory Committee composed of the research advisor and 3 to 5 others.
  • Scientists meet with student regularly to monitor progress.
CBI SPECIAL EVENTS
  • Annual Poster Sessions attended by students and faculty in the Chemistry-Biology Interface Program to discuss their research in an informal setting.
  • Weekly Seminar
  • Student-invited speakers
CBI MULTIDISCIPLINARY FACULTY
Forty-One University of Delaware faculty drawn from the Departments of Chemistry and Biochemistry, of Chemical Engineering, of Biological Sciences, of Animal and Food Sciences, of Plant and Soil Sciences, and of Materials Science and Engineering.
CBI NUTS AND BOLTS
The program is coordinated by a Steering Committee composed of Roberta F. Colman (Program Director, Biochemistry), Abraham M. Lenhoff (Associate Program Director, Chemical Engineering), John T. Koh (Organic Chemistry), Pamela J. Green (Plant & Soil Sciences), Daniel T. Simmons (Biological Sciences), Joel Schneider (Organic Chemistry) and Colin Thorpe (Biochemistry).

 

CBI ADMISSION

By application to the Department of Chemistry and Biochemistry, to the Department of Chemical Engineering, to the Department of Biological Sciences, or directly to the Chemistry-Biology Interface Graduate Program. Acceptance to a Ph.D. program in one of the three departments is required in order to be considered for admission to the CBI Program. Decisions on admission to the Chemistry-Biology Interface Program are made subsequently by the Steering Committee.

Because funding of the Chemistry-Biology Interface Program comes from the National Institutes of Health, admission to the CBI Program is limited to United States citizens and permanent residents.

 

PARTICIPATING FACULTY
ROBERTA F. COLMAN
Program Director (Chemistry and Biochemistry): Enzymology of Dehydrogenases and Glutathione S-transferases; Affinity Labeling and Mutagenesis of Adenylosuccinate Lyase and other Nucleotide Binding Enzymes
MACIEK R. ANTONIEWICZ Metabolic Flux Analysis; Systems Biology; Computational Tools for Quantifying Cellular Physiology BRIAN BAHNSON (Biochemistry): Intermediates of Enzyme Reactions and Enzyme Motions in Catalysis Viewed by X-ray Crystallography
THOMAS P. BEEBE, JR.(Analytical Chemistry): Measurement of Ligand - Receptor Interactions in Neurons Growing on Tailored Biomaterial Surfaces JOAN BURNSIDE (Animal & Food Sciences): Regulation of Gene Expression by Growth Hormone and Cytokines DANIEL D. CARSON (Biology): Extracellular Matrix Expression and Function; Reproductive, Developmental and Cancer Biology
JUNGHUEI CHEN (Biochemistry): Mechanism of Recombination in Both Prokaryotes and Eukaryotic Systems CARLTON R. COOPER (Biology): Prostate Metastasis to Bone and Cell Adhesion PATRICIA A. DELEON (Biology): Reproductive Genetics, Genomics, Sperm Proteomics, Male Infertility, Spermatogenesis, Molecular Aspects of Fertilization
MELINDA DUNCAN (Biology): Molecular Mechanisms of Vertebrate Eye Development M. CYNTHIA FARACH-CARSON (Biology): Biochemistry and Cell Biology of Bone Extracellular Matrix; Ca2+ Homeostasis JOSEPH M. FOX (Organic Chemistry): Synthetic Methodology and Organometallic Chemistry
ERIC M. FURST (Chemical Engineering): Cytoskeletal Structure — Function, Motor Protein Biophysics, Tissue Engineering PAMELA J. GREEN (Plant and Soil Sciences; Marine Studies): mRNA Stability; Ribonucleases; Functional Genomics of Noncoding and Peptide Coding RNAs XINQIAO JIA (Materials Science & Engineering) Novel Biomimetic Materials; Functional Biointerfaces; Tissue Engineering and Drug Delivery
MURRAY V. JOHNSTON (Analytical Chemistry): Biological Mass Spectrometry KRISTI L. KIICK (Materials Science & Engineering): Polymeric Materials for Cellular and Molecular Recognition ERIC B. KMIEC (Biological Sciences): Genetic Engineering and Gene Targeting in Plant and Mammalian Cells
JOHN T. KOH (Bioorganic Chemistry): Chemical Biology of Nuclear and Steroid Hormone Receptors KELVIN H. LEE (Chemical Engineering) Proteomics. Gene Expression Profiling to identify Rate-limiting Steps in Protein Secretion Pathways JUNG-YOUN LEE (Plant & Soil Sciences) Molecular Mechanisms and Components of Cell-Cell Communication
ABRAHAM M. LENHOFF (Chemical Engineering): Separation Processes; Protein Molecular Biophysics, Protein Thermodynamics ROBIN W. MORGAN (Animal & Food Sciences): Molecular Biology of Marek's Disease Virus, an Oncogenic Avian Herpes Virus ULHAS P. NAIK (Biology): Signaling Through Cell Adhesion Molecules
SHARON L. NEAL (Analytical Chemistry): Fluorescence Probe Kinetics in Biomembrane Models ELEFTHERIOS TERRY PAPOUTSAKIS (Chemical Engineering): Metabolic Flux Analysis; Metabolic Engineering and Genomics; Stem-Cell Engineering DARRIN J POCHAN (Materials Science & Engineering) Materials via Self Assembly; Nanotechnology; New Biomaterials; Bio-inorganic organic Hybrids
TATYANA POLENOVA (Physical Chemistry) Biophysics and Structural Biology of Protein Interfaces; Protein Assemblies, and Metallo-proteins; Biomolecular Solid-State NMR Spectroscopy CHARLES RIORDAN (Inorganic Chemistry): Synthetic and Mechanistic Models for Nickel and Zinc Sites in Proteins; Organometallic Drug Design CHRISTOPHER J. ROBERTS (Chemical Engineering): Protein Aggregation; Prediction of Protein Degradation and Shelf Life; Protein Preservation
ANNE ROBINSON (Chemical Engineering): Molecular and Cellular Engineering; Engineering Protein-Protein Interactions in vivo and in vitro for Improved Protein Production SHARON ROZOVSKY (Biochemistry and Biophysics) Function of Membrane Proteins; Lipid-Protein Interactions; Membrane Biophysics JOEL P. SCHNEIDER (Bioorganic Chemistry): Peptide and protein de novo Design. Synthesis of Peptide Receptors, Probes and Biomaterials.
ERICA M SELVA (Biology): Genetic and Molecular Control of Signal Transduction during Drosophila Development ROBERT A. SIKES (Biological Sciences): Prostate Development; Prostate Cancer Development, Progression and Testing of Novel Therapeutic Agents DANIEL T. SIMMONS (Biology): Virology and Molecular Biology; Structure and Function of SV40 T Antigen and Tumor Suppressor Protein p53
MILLICENT O. SULLIVAN (Chemical Engineering) Design of Polymeric Materials for Improved Drug and Gene Transport; Engineering of Cell-Biomaterial Interactions DOUGLASS F. TABER (Organic Chemistry): Stereoselective Synthesis of Complex Physiologically Active Natural Products; Computational Organometallic Chemistry COLIN THORPE (Biochemistry): Enzymology of Flavoproteins in Fatty Acid Metabolism; Protein Disulfide Bond Formation
ZHIHAO ZHUANG (Biochemistry) Chemical Biology. Molecular Mechanism of Protein Machineries in DNA Damage Repair and Tolerance Pathways, particularly the Regulation of these pathways by Post-Translational Protein Modification by Ubiquitination and Sumoylation NEAL J. ZONDLO (Bioorganic Chemistry): Functional Molecular Recognition by Designed Architectures  
For further information call Dr. Roberta F. Colman
at (302) 831-2973 or
email rfcolman@udel.edu
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Last update, February 11, 2008.