CBI Students

I came to Delaware specifically because of the CBI program.  I liked the multi-disciplinary aspects of the program.  It was a wonderful experience to rotate through a number of labs.  […]  For me the whole program was a very positive experience.”

--Erin Bernberg, Associate Scientist, Delaware Biotechnology Institute.

Eric Levenson (CBC) 

I am currently working on synthesizing innate immune system stimulating, immune complex mimetics, to study autoimmune disease in the Kiick/Zhuang Labs.

Stephanie Schaefer (CBC)

Working in the Thorpe Lab on the mechanism of disulfide bond insertion into reduced unfolded proteins

Benjamin Israel (CBC)

I am currently working in Dr. Colin Thorpe's lab on the expression and characterization of Quiescin sulfhydryl oxidase 2 (QSOX2).

Patrick McNeely (CBE)

Working in the Robinson lab toward a GPCR folding, trafficking and signaling assay.  The G protein-coupled receptor (GPCR) family makes up the largest group of cellular signaling proteins in humans, responding to stimuli as diverse as hormone, photons, and small-molecules.

Morgan Urello (CBE)

Working in the Sullivan and Kiick labs, Morgan is engineering a DNA-modified collagen I scaffold in order to facilitate wound repair.  DNA encoding vascular endothelial growth factor (VEGF) will be condensed using a cationic polymer and attached to the collagen I matrix using a collagen mimetic peptide.

Mackenzie Lauro (CBC)

Working in the Grimes and Bahnson labs on the expression and purification of the human innate immune receptor Nod2 in an E. coli system.  Mackenzie will then attempt to determine the crystal structural and functional aspects of the protein.

Devin Hudson (CBC)
Involved in multiple research projects with different goals in the Thorpe lab.  He is currently conducting a mutational study of active site residues near the isoalloxazine ring of flavin adenine dinucleotide, to further understand the oxygen evolution process of sfALR.

Karl Franke (BISC)

Working outside his home department of Biological Sciences, with Dr. Green from Plant & Soil Sciences, on the genome-wide analysis of miRNA targets in Brachypodium and Biomass Energy Crops.  Brachypodium distachyon is a relatively new model organism for biomass energy crops such as Sorghum bicolor and Pancium virgatum (switchgrass), as well as a few food crops such as wheat and barley.

Yiben Wang (CBC)

Working in the Grimes lab on labeling the bacterial cell wall with unnatural sugars in order to understand how and where the fragments of  the bacterial cell wall that stimulate the innate immune system are generated in vivo.

Nikodimos Gebreselassie (CBE)

Working in the Antoniewicz lab to develop approaches to analyze the flux distribution of co-culture systems require over-expressed and  separation of reporter proteins before the analysis of the labeling patterns of the amino acids to infer the flux distribution.

Erik Munsell (CBE)

Working in the Sullivan lab, Erik’s goal is to develop biologically relevant non-viral systems for enhanced gene delivery.  Specifically, his project focuses on the design of a higher ordered histone-mimetic delivery system with enhanced tailorability and effectiveness in vitro.

Kevin Cannon (BISC)

Working in the Jia lab on a collaborative project working on engineering an artificial salivary gland with Dr. Robert Witt, Dr. Randy Duncan, and Dr. Xinqiao Jia.

Christopher Long (CBE)

Working in the Antoniewicz lab with a focus on the study of the metabolisms of E. coli gene knockout strains using 13C Metabolic Flux Analysis.  This work will provide important data necessary for improving models of the wild type and knockout metabolism, as well as our understanding of E. coli metabolic regulation.

Christine Ott (CBC)

Working with Dr. Zhuang studying deubiquitinating enzymes and compounds to inhibit these enzymes.

Amy Schaefer (CBC)

Working in Grimes Lab on the characterization of binding between ATP and NOD2.

Brandy Menges (BISC)

Working in the Boyd lab on V. parahaemolyticus, which is a moderate halophile with an absolute requirement for salt and inhabits brackish waters and is ubiquitous within its environment, having the ability to colonize a wide range of host including crustaceans, fish, mollusks, and humans, and can be found as a free living organism.

Robert Panish (CBC)

Working in the Fox group focused on the first enantioselective formation substituted bicyclobutane esters and the subsequent reaction with Grignard reagents in the presence of Cu(I) to afford enantiopure cyclobutanes containing a high degree of stereochemistry and substitution.  This bicyclobutanation/conjugate addition chemistry will be applied to the total synthesis of Pauferrol A.

Matthew Rehmann (CBE)

Working in the Kloxin lab on a project involving two goals: (1) development of a step-growth, dynamically tunable poly(ethylene glycol) cell culture system, and (2) application of this system to mesenchymal stem cell culture, with a focus on chemical signals that promote differentiation to ligament fibroblasts.

Kyle Doolan (CBE)

Research in the Colby Lab focusing on the development of a cell-based antibody delivery platform for the treatment of neurodegenerative disease.

Nick Levy (CHEG)

Working in the Lenhoff lab on a project aimed to identify specific HCP that form product related impurities at realistic process conditions.  The experimental method used involves commercial mAbs that are immobilized onto chromatographic media.  CHO cell culture supernatant is then pulsed through a column containing the immobilized mAb.  Late eluting proteins have stronger attractive forces towards the immobilized mAb and are thus more likely to form product associations.

Sara Martin (CBC)

Work in the D. Watson Lab is aimed at forming styryl silylethers via a Pd catalyzed silyl Heck Reaction.

Jean-Bernard “JB” Lubin (BISC)

Research in the Boyd lab focusing on evolutionary and biochemical approaches to understanding divergence in sialic acid metabolism Vibrio vulnificus.

Natalee Smith (CBC)

Working in the Fox lab studying the reactivity of larger trans-cyclic enones, which are formed in situ upon irradiation of their cis isomers.  The hope is that some selectivity will be obtained in the subsequent conjugate addition to the trans isomer of the cyclic enone that would not have necessarily arisen from the same reaction with the cis isomer without the aid of a catalyst.

Kristen DeMeester (CBC)

Currently performing lab rotations.

Jason Cargill (CBE)

Currently performing lab rotations.

Josephine Chiu (CBE)

Currently performing lab rotations.

Matthew Fritz (CBC)

Currently performing lab rotations.

Nathan McDonald (BISC)

Currently performing lab rotations.

Emily Hartzell (CBE)

Currently performing lab rotations.