| Bahnson Lab - Structural Enzymology |
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We
are exploring the fascinating catalytic power of enzymes with a focus
on two related areas of interest: (i) x-ray crystallography is used to
solve structures of substrate complexes and intermediates of enzyme
catalyzed reactions and
(ii) understanding the role of evolved ordered enzyme motions in
catalysis. This work will provide more thorough answers to the
questions: how do precise interactions of all the active site side
chains, metal ions, bound water molecules and intermediates contribute
to catalysis? what does the transition state look like for a chemical
step between two observable enzyme-intermediate structures? and how do
evolved ordered motions of the entire enzyme play a part in catalysis?
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Contact - Brian J. Bahnson |
 lab picture taken spring of 2012
click here for another pic |
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