Research Programs

Sort by Subject Area | Sort Alphabetically

Shortcuts to:
Animal Physiology, Cancer Biology, Cell and Extracellular Matrix Biology, Developmental Biology, Ecology and Evolution, Microbiology and Virology, Molecular Biology and Genetics, Science Education

Animal Physiology

Name	Description
Akins, Robert	Development and regulation of cellular organization and function in striated muscle.
Carson, Daniel	Mammalian embryo implantation and development, role of proteoglycans and mucins in cancer progression.
DeLeon, Patricia	Reproductive genetics, genomics, and sperm proteomics.
Duncan, Melinda	Eye development.
Duncan, Randall	Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Farach-Carson, Mary C.	Molecular and cell biology of bone cells and bone extracellular matrix.
Kirn-Safran, Catherine	Skeletogenesis in mice.
Laverty, Gary	Epithelial transport systems in cultured tissues.
Naik, Ulhas	Role of adhesion molecules in vascular biology.
Rajasekaran, Ayyappan	Regulation of epithelial junctional complexes by ion transporters and cell adhesion molecules.
Rajasekaran, Sigrid	Link between obesity and cancer.
Rogers, Robert	Cardiovascular and respiratory control; computational neurophysiology.
Schanen, Carolyn	Cellular mechanisms regulating expression and function of chromatin proteins in nerve and bone cells.
Sikes, Robert	Mouse prostate development and the development and progression of human prostate cancer.
Skopik, Steven	Biology education, development of introductory biology laboratory experiences.
Stephens, Gregory	Catabolism of high density lipoproteins (HDL) in turtles.
Taylor, Malcolm	Environmental and endocrine control of reproduction in estuarine fishes.
Twiss, Jeffery	Effects of neuronal activity and environmental stimuli on nerve regeneration and neural repair.
Usher, David	The relationship of obesity to metabolic syndrome and heart disease.
Wagner, Roger	The role of pericytes and endothelial cells in the function of microvessels and capillaries.

Go to top of page

Cancer Biology

Name	Description
Carson, Daniel	Role of extracellular matrix in cancer growth, metastasis and disease progression.
Cooper, Carlton	The role of cell adhesion in prostate cancer preferential metastasis to bone.
Dodge, George	Role of extracellular matrix and their proteases in cancer, cell migration and apoptosis.
Farach-Carson, Mary C.	Extracellular matrix and hormonal influences on cancer metastasis to bone.
Galileo, Deni	Adhesion molecules that influence glioma and breast cancer cell motility, invasiveness, and metastasis in a chick xenograft model.
McLane, Mary Ann	Molecular mechanisms involved in cancer metastasis.
Naik, Ulhas	Tumor angiogenesis and tumor metastasis using animal models, focusing on breast and prostate cancer.
Rajasekaran, Ayyappan	Molecular mechanisms involved in the regulation of epithelial to mesenchymal and mesenchymal to epithelial transitions.
Rajasekaran, Sigrid	Link between obesity and cancer.
Sikes, Robert	Human prostate cancer progression, metastatic cell interaction with bone and therapeutic intervention.
Simmons, Daniel	Malignant transformation by papovaviruses.
van Golen, Kenneth	Role of RhoC GTPase in conferring a metastatic phenotype to aggressive cancers.

See also our partners in translational cancer research at the Christiana Care Cancer Research Program.

Go to top of page

Cell and Extracellular Matrix Biology

Name	Description
Akins, Robert	Cell:cell interactions, signaling cascades, and cell migration in tissue engineering and regenerative therapies.
Carson, Daniel	Mammalian embryo implantation and development, role of proteoglycans and mucins in cancer progression.
Cooper, Carlton	The role of cell adhesion in prostate cancer preferential metastasis to bone.
Dodge, George	Cartilage extracellular matrix, tissue engineering of cartilage and bone substitutes.
Duncan, Melinda	The function of the lens capsule and the regulation of transcription by cell signaling.
Duncan, Randall	Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Farach-Carson, Mary C.	Molecular and cell biology of bone cells and bone extracellular matrix.
Galileo, Deni	Cell division, death, migration, and differentiation in early development of the vertebrate brain. Cancer cell biology and interaction with ECM.
Kirn-Safran, Catherine	Osteoblast, chondrocyte, and odontoblast differentiation.
Laverty, Gary	Epithelial transport systems in cultured tissues.
Naik, Ulhas	Signaling through adhesion molecules during angiogenesis and platelet aggregation.
Rajasekaran, Ayyappan	Modulation of tumor microenvironment by cell adhesion molecules.
Rajasekaran, Sigrid	Therapeutic and diagnostic potential of intracellular sodium.
Rogers, Robert	Electrophysiology of excitable membranes.
Selva, Erica	Genetic and molecular control of signal transduction during Drosophila development.
Sherrier, Janine	Modification of the plant cell wall during interactions with microbes.
Sikes, Robert	Mouse prostate development and the development and progression of human prostate cancer.

Go to top of page

Developmental Biology

Name	Description
Akins, Robert	Cardiac morphogenesis and the development of congenital heart malformations.
Burnside, Joan	Avian genomics.
Carson, Daniel	Embryo-maternal interactions.
DeLeon, Patricia	Genetics of sperm maturation and function.
Dodge, George	Extracellular matrix gene expression in development of the skeleton; cartilage development.
Duncan, Melinda	Eye development.
Duncan, Randall	Signal transduction of mechanical and hormonal stimulation in the development and maintenance of bone and cartilage.
Farach-Carson, Mary C.	Bone and cartilage formation.
Galileo, Deni	Early vertebrate brain development.
Kirn-Safran, Catherine	Mineralized tissue embryogenesis.
Molloy, George	Transcriptional and translational control in brain development.
Naik, Ulhas	Cardiac development and hypertrophy.
Rajasekaran, Ayyappan	Role of epithelial junctional complexes and ion transporters in development.
Selva, Erica	Control of Wnt and hedgehog signaling in Drosophila development.
Sherrier, Janine	Development of nitrogen-fixing root nodules; development of pathogenic root knots.
Sikes, Robert	Development of the prostate gland.
Twiss, Jeffery	Axon growth mechanisms and neuronal survival/signaling.
Usher, David	Development of adipose tissue.

Go to top of page

Ecology and Evolution

Name	Description
Boyd, Fidelma	Molecular evolution and pathogenesis of bacteria.
Duncan, Melinda	Evolutionary origins of refractive proteins.
Hanson, Thomas	Evolution of autotrophy, tundra soil microbial ecology, metaproteomics/genomics.
Karlson, Ronald	Large-scale ecology of coral assemblages, the effects of disturbance on coral assemblages.
McDonald, John	Effects of natural selection on nuclear genes.
Smith, David	Sulfur and nitrogen cycles in bacteria residing in salt marsh environments.
Tallamy, Douglas	Luperine chrysomelid beetle interactions with toxic cucurbitacin triterpenes.

Go to top of page

Microbiology and Virology

Name	Description
Boyd, Fidelma	Molecular evolution and pathogenesis of bacteria.
Galileo, Deni	Retroviruses and their use as vectors, including lentiviruses.
Hanson, Thomas	Photosynthetic metabolism, biogeochemistry, applied microbiology.
Herson, Diane	Physiology of organisms which carry out bioremediation, Helicobacter-pylori in water.
Keeler, Calvin	Avian influenza and avian herpesviruses - host-pathogen interactions, vaccines, and diagnostics.
Kmiec, Eric	Molecular biology of DNA repair and its applications to genetic medicine, gene therapy and genomics.
Parent, Michelle	Yersinia - host-pathogen interaction.
Sherrier, Janine	The role of bacterial LPS in nitrogen-fixing root nodule development.
Simmons, Daniel	Mechanism of DNA replication.
Smith, David	Sulfur and nitrogen cycles in bacteria residing in salt marsh environments.

Go to top of page

Molecular Biology and Genetics

Name	Description
Akins, Robert	Heterotypic cell interactions in the control of gene expression, multi-cellular organization, and contractile function in striated muscle.
Boyd, Fidelma	Molecular evolution and pathogenesis of bacteria.
Burnside, Joan	Identification of hormone receptor genes in poultry.
Carson, Daniel	Mammalian embryo implantation and development, role of proteoglycans and mucins in cancer progression.
Czymmek, Kirk	Fungal cell biology and plant pathogenesis.
DeLeon, Patricia	Reproductive genetics, genomics, and sperm proteomics.
Dodge, George	Chondrocyte gene regulation and disease, alternative-splicing of ECM genes.
Duncan, Melinda	The transcriptional consequences of cell signaling during development.
Farach-Carson, Mary C.	Molecular and cell biology of bone cells and bone extracellular matrix.
Galileo, Deni	Migration, survival, and differentiation of vertebrate brain and of brain tumor cells.
Hanson, Thomas	Genetic analysis of metabolism, expanding genetic toolkits in novel microbes.
Herson, Diane	Physiology of organisms which carry out bioremediation, Helicobacter-pylori in water.
Hodson, Robert	Molecular evolution of apolipoprotein genes.
Keeler, Calvin	Genomic approaches to the study of the innate immune system.
Kirn-Safran, Catherine	Gene targeting by homologous recombination.
Kmiec, Eric	Molecular biology of DNA repair and its applications to genetic medicine, gene therapy and genomics.
McLane, Mary Ann	Molecular mechanisms involved in cancer metastasis.
Molloy, George	Control of animal cell growth and differentiation related to neuronal and brain glial cells.
Morgan, Robin	Molecular biology of Marek's disease.
Naik, Ulhas	Signaling cross-talk between growth factor receptors and adhesion molecules: use of transgenic and knockout mice.
Rajasekaran, Ayyappan	Role of Na,K-ATPase in cell signaling.
Rogers, Robert	Functional genomics and computational biology.
Schanen, Carolyn	Genetics of autism and speech disorders, epigenetic regulation of gene expression by DNA methylation, chromosomal rearrangements.
Schmidt, Carl	Bioinformatics and avian genomics.
Selva, Erica	Genetic and molecular control of signal transduction during Drosophila development.
Sherrier, Janine	Analysis of the small RNA transcriptome of Medicago truncatula.
Sikes, Robert	Mouse prostate development and the development and progression of human prostate cancer.
Simmons, Daniel	Mechanism of DNA replication.
Twiss, Jeffery	Subcellular localization of neuronal mRNAs and translational control.
Usher, David	The relationship of obesity to metabolic syndrome and heart disease.

Go to top of page

Science Education

Name	Description
Allen, Deborah	Active and collaborative learning strategies and materials; learning communities.
Fifield, Steven	Cultural studies of science; how knowledge, meaning, and identity are enacted in science education.
Hodson, Robert	Biology education with special emphasis on development of introductory biology laboratory investigations and computer networking.
Schmieg, Florence	The effect of Problem-Based-Learning (PBL) strategies on educational outcomes.
Skopik, Steven	Biology education, development of introductory biology laboratory experiences.
Usher, David	Affect of undergraduate research on educational outcomes; recruitment and retention of underrepresented minorities in the sciences.

Go to top of page

Research
» Research Programs (Subject Area)

E-mail link to this page
Printer-friendly format