Thomas L. Bauer II, M.D.

Adjunct Assistant Professor
Thoracic Surgeon, Helen F. Graham Cancer Center
Clinical Assistant Professor of Surgery, Thomas Jefferson University

Contact

Bauer

Helen F. Graham Cancer Center
4701 Ogletown Stanton Road
Suite 1204
Newark, DE 19713

Phone: (302) 623-4530
Fax: (302) 623-4522
E-mail: tbauer@christianacare.org

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Education

B.S.: Dickinson College
M.D.: Thomas Jefferson University

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Research Interests

As a thoracic surgeon, I am interested in the use of advanced computer aided 3D imaging of the chest cavity and its organs, including the lungs, utilizing the "CAVE" at the Delaware Biotechnology Institute. I also am collaborating with biologists and genetics faculty at the University of Delaware to investigate DNA damage repair pathways and their role in augmenting cell death with chemotherapy.

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Current Projects

• 3D reconstruction of CT scans for virtual surgery training and education (project at DBI with Karl Steiner).
• The use of oligonucleotides in treating esophageal and lung cancer cell lines (project at DBI with Eric Kmiec).
• Commuter analysis of lung abnormalities on CT scans (project at UD with Chandra Kambhamettu).
• Thoracic oncology summer clerkship at HFGCC. Students learn to workup, diagnosis, treat and care for patients with thoracic malignancies while completing a clinical research project.

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Selected Publications

TL Bauer and KV Steiner. Virtual Bronchoscopy - Clinical Applications and Limitations. Medical Oncology Clinics of North America, April 2007.

Steward NA, Bauer TL, Margules A, and Cephas A. Assessing the Impact of Smoke-related Illness on Smoking Cessation Efforts. Delaware Medical Journal, 49(4):151-156, 2007.

Keeney S and Bauer TL. Epidemiology of Adenocarcinoma of the Esophagogastric Junction. Surgical Oncology Clinics of North America, 15:687-696, 2006.

International Early Lung Cancer Action Program Investigators. Women's Susceptibility to Tobocco Carcinogens: an Update. JAMA, 296:180-184, 2006.

International Early Lung Cancer Action Program Investigators. CT Screening for Lung Cancer: The relationship of disease stage to tumor size. Archives of Internal Medicine, 166:321-325, 2006.

Henschke CI on behalf of I-ELCAP Investigators. CT Screening for Lung Cancer: Update 2005. Surgical Oncology Clinics of North America, 14:761-776, 2005.

Khan AA, Bauer TL, Garcia MJ, Panasuk DB, and Davies AL. Angiographic Embolization of a Traumatic Pulmonary Pseudoaneurysm. Ann Thor Surgery, 79:2136-2138, 2005.

Bauer TL. Lung Cancer Screening. Hematol Oncol Clin N Am, 19:209-217, 2004.

Panasuk, DB, Bauer, TL, Davies AL, Schneider C, and Flynn C. Common Malignancies with Uncommon Sites of Presentation: Anterior Mediastinal Rhabdomyosarcoma. J Clin. Oncology, 21:4455-4459, 2003.

Konkle BA, Bauer TL, Arepally G, Clines DB, Poncz M, McNulty S, Edie RN, and Mannion JD. The incidence of anti-heparin antibodies in cardiopulmonary bypass using porcine and bovine heparin, a prospective study. Ann Thor Surg, 71:1920-1924, 2001.

O'Brien J, Shi Y, Fard A, Bauer T, and Zalewski A. Wound Healing Around and Within Saphenous Vein Bypass Grafts. J Thorac Cardiovasc Surg, 114:38-45, 1997.

Ahmad F, Considine RV, Bauer TL, Ohannesian JP, Mario CC, and Goldstein BJ. Improved Sensitivity in Obese Subjects Following Weight Loss is Accompanied by Reduced Protein Tyrosine Phosphatases in Adipose Tissue. Metabolism, 46(10):1140-1145, 1997.

Bauer TL, Arepally G, Konkle BA, Mestichelli B, Shapiro SS, Clines DB, Poncz M, McNulty S, Amiral J, Hauk WW, Edie RN, and Mannion JD. Prevalence of Heparin-associated Antibodies without Thrombosis in Patients Undergoing Cardiopulmonary Bypass Surgery. Circulation, 95(5):1242-1246, 1997.

Bailey WF, Magno MG, Bauer TL, Mannion JD. Heparin and Basic Fibroblast Factor are Associated with Preservation of Latissimus Cardiomyoplasties in Goats: A Retrospective Study. Journal of Cardiac Surgery, 11(4):247-55, 1996.

Considine RV, Nyce MR, Morales LM, Magosin SA, Sinha MK, Bauer TL, Rosato EL, Colberg J, and Caro JF. Paracrine Stimulation of Preadipocyte-enriched Cell Cultures by Nature Adipocytes. Amer J of Physiology, 270(5 Pt 1):E895-899, 1996.

Considine RV, Considine, EL, Williams CJ, Nyce MR, Zhang R, Opentanova JP, Kolaczynski JW, Bauer TL, Moore JH, and Caro JF. Variation in the Human ob Gene Coding Region. Biochemical & Biophysical Research Communications, 320(3):735-739, 1996.

Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, et al. Serum Immunoreactive-leptin Concentrations in Normal-weight and Obese Humans. New England Journal of Medicine 334(5):292-295, 1996.

Mannion JD, Blood V, Bailey W, Bauer TL, Magno MG, DiMeo F, Epple A, and Spinale FB. The Effect of Basic Fibroblast Growth Factor on the Blood Flow and Morphologic Features of a Latissimus Dorsi Cardioplasty. Journal of Thoracic and Cardiovascular Surgery, 111(1):19-28, 1996.

Considine RV, Considine EL, Williams CJ, Nyce MR, Magosin SA, Bauer TL, Rosato EL, Colberg J, and Caro JF. Evidence Against Either a Premature Stop Codon or the Absence of Obese Gene aRMNA in Human Obesity. Journal of Clinical Investigation. 95(6):2986-2988, 1995.

Minchenko A, Salceda S, Bauer T, and Caro J. Hypoxic regulatory Elements of the Human Vascular endothelial Growth Factor Gene. Cell And Mol Bio Res, 40(1):35-39, 1994.

Minchenko A, Bauer T, Salceda S, and Caro J. Hypoxic Stimulation of Vascular Endothelial Growth Factor (VEGF) Expression in Vitro and in Vivo. Laboratory Investigation, 71(3):374-379, 1994.

Singer RL, Mannion JD, Bauer TL, Armenti FR, and Edie RN. Complications from Heparin Induced Thrombocytopenia in Patients Undergoing Cardiopulmonary Bypass. Chest, 104:1436-1440, 1993.

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