Delaware Chapter, ASA
Dinner Meeting: Feburary 2002
We conducted a nested case (n=177) control (n=550) study to assess the relationship between retrospective magnetic field measures and clinical miscarriage. We also conducted a prospective sub-study of 219 participants of the same parent cohort to determine if prospective exposure assessments were similar to the retrospective assessments. We evaluated wire codes, area measures and three personal meter metrics: 1) the average difference between consecutive levels (a rate of change metric, RCM); 2) the maximum level; 3) the time weighted average (TWA).
For wire codes and area measures we found little association. For the personal metrics we found positive associations. Adjusted odds ratios and 95% confidence intervals comparing higher to the lowest exposure quartile were, respectively: 3.1 (1.6-6.0), 2.3 (1.2-4.4), and 1.5 (0.8-3.1) for the RCM; 2.3 (1.2-4.4), 1.9 (1.0-3.5), and 1.4 (0.7-2.8) for the maximum value; and 1.7 (0.9-3.3), 1.7 (0.9-3.3), and 1.7 (0.9-3.3) for the TWA. The odds ratio conveyed by being above a 24 hr TWA of 2 mG was 1.0 (0.5-2.1). Prospective and retrospective measures were poorly correlated. Nonetheless, the prospective sub-study results were consistent with the nested study results. One should confirm these findings and identify exposure sources for these metrics.
Reservations to Stephen Bingham by Monday, February 18, 2002.
Please note: Be sure to RSVP by this date, to assure a meal is reserved for you.